LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 765 | 1002 | 3148 | 0.3185 | 0.1417 |
Hs 578T | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 765 | 972 | 3148 | 0.3087 | 0.1239 |
Hs 578T | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 765 | 972 | 3148 | 0.3090 | 0.1247 |
Hs 578T | AZD8330 | 10 | uM | LJP5 | 72 | hr | 765 | 916 | 3148 | 0.2912 | 0.0925 |
Hs 578T | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 765 | 2905 | 3148 | 0.9228 | 0.9226 |
Hs 578T | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 765 | 2904 | 3148 | 0.9224 | 0.9224 |
Hs 578T | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 765 | 2818 | 3148 | 0.8951 | 0.8943 |
Hs 578T | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 765 | 2711 | 3148 | 0.8613 | 0.8587 |
Hs 578T | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 765 | 1568 | 3148 | 0.4981 | 0.4213 |
Hs 578T | TGX221 | 10 | uM | LJP5 | 72 | hr | 765 | 2016 | 3148 | 0.6405 | 0.6077 |
Hs 578T | GSK1059615 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3004 | 3148 | 0.9542 | 0.9545 |
Hs 578T | GSK1059615 | 0.04 | uM | LJP6 | 72 | hr | 765 | 2852 | 3101 | 0.9198 | 0.9189 |
Hs 578T | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 765 | 2759 | 3148 | 0.8765 | 0.8748 |
Hs 578T | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 765 | 2413 | 3101 | 0.7781 | 0.7664 |
Hs 578T | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 765 | 2030 | 3148 | 0.6448 | 0.6131 |
Hs 578T | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 765 | 1994 | 3101 | 0.6425 | 0.6058 |
Hs 578T | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 765 | 1349 | 3148 | 0.4285 | 0.3202 |
Hs 578T | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 765 | 1467 | 3101 | 0.4730 | 0.3803 |
Hs 578T | GSK1059615 | 3.33 | uM | LJP5 | 72 | hr | 765 | 528 | 3148 | 0.1679 | -0.1684 |
Hs 578T | GSK1059615 | 3.33 | uM | LJP6 | 72 | hr | 765 | 1028 | 3101 | 0.3313 | 0.1567 |
Hs 578T | GSK1059615 | 10 | uM | LJP5 | 72 | hr | 765 | 590 | 3148 | 0.1875 | -0.1215 |
Hs 578T | GSK1059615 | 10 | uM | LJP6 | 72 | hr | 765 | 698 | 3101 | 0.2255 | -0.0480 |
Hs 578T | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 765 | 3057 | 3148 | 0.9711 | 0.9714 |
Hs 578T | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 765 | 3068 | 3148 | 0.9746 | 0.9747 |
Hs 578T | Brivanib | 0.37 | uM | LJP5 | 72 | hr | 765 | 3069 | 3148 | 0.9750 | 0.9751 |