LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 765 | 2041 | 3101 | 0.6578 | 0.6245 |
Hs 578T | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 765 | 1207 | 3101 | 0.3891 | 0.2528 |
Hs 578T | QL-XII-47 | 10 | uM | LJP6 | 72 | hr | 765 | 412 | 3101 | 0.1329 | -0.2644 |
Hs 578T | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 765 | 1096 | 3101 | 0.3534 | 0.1949 |
Hs 578T | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 765 | 974 | 3101 | 0.3143 | 0.1266 |
Hs 578T | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 765 | 867 | 3101 | 0.2797 | 0.0640 |
Hs 578T | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 765 | 781 | 3101 | 0.2520 | 0.0102 |
Hs 578T | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 765 | 698 | 3101 | 0.2252 | -0.0443 |
Hs 578T | Torin1 | 10 | uM | LJP6 | 72 | hr | 765 | 482 | 3101 | 0.1553 | -0.2049 |
Hs 578T | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 765 | 1013 | 3148 | 0.3218 | 0.1469 |
Hs 578T | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 765 | 813 | 3148 | 0.2582 | 0.0301 |
Hs 578T | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 765 | 575 | 3148 | 0.1829 | -0.1304 |
Hs 578T | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 765 | 535 | 3148 | 0.1701 | -0.1605 |
Hs 578T | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 765 | 495 | 3148 | 0.1574 | -0.1919 |
Hs 578T | Torin2 | 10 | uM | LJP5 | 72 | hr | 765 | 397 | 3148 | 0.1263 | -0.2752 |
Hs 578T | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 765 | 2191 | 3101 | 0.7063 | 0.6834 |
Hs 578T | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 765 | 2079 | 3101 | 0.6701 | 0.6393 |
Hs 578T | WZ-4-145 | 0.37 | uM | LJP6 | 72 | hr | 765 | 1915 | 3101 | 0.6173 | 0.5750 |
Hs 578T | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 765 | 1579 | 3101 | 0.5090 | 0.4313 |
Hs 578T | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 765 | 1509 | 3101 | 0.4866 | 0.4000 |
Hs 578T | WZ-4-145 | 10 | uM | LJP6 | 72 | hr | 765 | 713 | 3101 | 0.2301 | -0.0341 |
Hs 578T | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 765 | 483 | 3148 | 0.1534 | -0.2022 |
Hs 578T | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 765 | 479 | 3148 | 0.1521 | -0.2056 |
Hs 578T | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 765 | 447 | 3148 | 0.1421 | -0.2312 |
Hs 578T | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 765 | 412 | 3148 | 0.1310 | -0.2619 |