LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Palbociclib
0.37
uM
LJP6
 72
hr
 765 1806 3101 0.5824 0.5302
Hs 578T Palbociclib
1.11
uM
LJP6
 72
hr
 765 1554 3101 0.5009 0.4198
Hs 578T Palbociclib
3.33
uM
LJP6
 72
hr
 765 1511 3101 0.4875 0.4010
Hs 578T Palbociclib
10
uM
LJP6
 72
hr
 765 1377 3101 0.4440 0.3378
Hs 578T PF562271
0.04
uM
LJP6
 72
hr
 765 2769 3101 0.8928 0.8908
Hs 578T PF562271
0.12
uM
LJP6
 72
hr
 765 2502 3101 0.8065 0.7976
Hs 578T PF562271
0.37
uM
LJP6
 72
hr
 765 2251 3101 0.7257 0.7061
Hs 578T PF562271
1.11
uM
LJP6
 72
hr
 765 1969 3101 0.6348 0.5967
Hs 578T PF562271
3.33
uM
LJP6
 72
hr
 765 1526 3101 0.4921 0.4077
Hs 578T PF562271
10
uM
LJP6
 72
hr
 765 461 3101 0.1489 -0.2215
Hs 578T PHA-793887
0.04
uM
LJP6
 72
hr
 765 1590 3101 0.5128 0.4368
Hs 578T PHA-793887
0.12
uM
LJP6
 72
hr
 765 1479 3101 0.4769 0.3860
Hs 578T PHA-793887
0.37
uM
LJP6
 72
hr
 765 1113 3101 0.3591 0.2043
Hs 578T PHA-793887
1.11
uM
LJP6
 72
hr
 765 790 3101 0.2549 0.0162
Hs 578T PHA-793887
3.33
uM
LJP6
 72
hr
 765 619 3101 0.1999 -0.1000
Hs 578T PHA-793887
10
uM
LJP6
 72
hr
 765 397 3101 0.1282 -0.2777
Hs 578T QL-X-138
0.04
uM
LJP6
 72
hr
 765 2546 3101 0.8210 0.8138
Hs 578T QL-X-138
0.12
uM
LJP6
 72
hr
 765 2301 3101 0.7420 0.7253
Hs 578T QL-X-138
0.37
uM
LJP6
 72
hr
 765 2050 3101 0.6611 0.6294
Hs 578T QL-X-138
1.11
uM
LJP6
 72
hr
 765 1711 3101 0.5517 0.4897
Hs 578T QL-X-138
3.33
uM
LJP6
 72
hr
 765 1463 3101 0.4717 0.3782
Hs 578T QL-X-138
10
uM
LJP6
 72
hr
 765 572 3101 0.1846 -0.1344
Hs 578T QL-XII-47
0.04
uM
LJP6
 72
hr
 765 2960 3101 0.9541 0.9536
Hs 578T QL-XII-47
0.12
uM
LJP6
 72
hr
 765 2805 3101 0.9043 0.9028
Hs 578T QL-XII-47
0.37
uM
LJP6
 72
hr
 765 2539 3101 0.8183 0.8104