LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 765 997 3101 0.3216 0.1400
Hs 578T WYE-125132
0.37
uM
LJP6
 72
hr
 765 923 3101 0.2976 0.0973
Hs 578T WYE-125132
1.11
uM
LJP6
 72
hr
 765 871 3101 0.2812 0.0664
Hs 578T WYE-125132
3.33
uM
LJP6
 72
hr
 765 875 3101 0.2824 0.0691
Hs 578T WYE-125132
10
uM
LJP6
 72
hr
 765 658 3101 0.2124 -0.0717
Hs 578T Barasertib
0.04
uM
LJP5
 72
hr
 765 1128 3148 0.3586 0.2095
Hs 578T Barasertib
0.12
uM
LJP5
 72
hr
 765 1128 3148 0.3584 0.2096
Hs 578T Barasertib
0.37
uM
LJP5
 72
hr
 765 1089 3148 0.3460 0.1890
Hs 578T Barasertib
1.11
uM
LJP5
 72
hr
 765 1005 3148 0.3194 0.1434
Hs 578T Barasertib
3.33
uM
LJP5
 72
hr
 765 945 3148 0.3003 0.1090
Hs 578T Barasertib
10
uM
LJP5
 72
hr
 765 863 3148 0.2742 0.0610
Hs 578T Vemurafenib
0.04
uM
LJP5
 72
hr
 765 3316 3148 1.0533 1.0516
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 765 3257 3148 1.0348 1.0338
Hs 578T Vemurafenib
0.37
uM
LJP5
 72
hr
 765 3287 3148 1.0441 1.0427
Hs 578T Vemurafenib
1.11
uM
LJP5
 72
hr
 765 3290 3148 1.0453 1.0439
Hs 578T Vemurafenib
3.33
uM
LJP5
 72
hr
 765 3014 3148 0.9575 0.9579
Hs 578T Vemurafenib
10
uM
LJP5
 72
hr
 765 1944 3148 0.6177 0.5793
Hs 578T Enzastaurin
0.04
uM
LJP5
 72
hr
 765 3127 3148 0.9934 0.9934
Hs 578T Enzastaurin
0.12
uM
LJP5
 72
hr
 765 3078 3148 0.9778 0.9781
Hs 578T Enzastaurin
0.37
uM
LJP5
 72
hr
 765 3051 3148 0.9693 0.9695
Hs 578T Enzastaurin
1.11
uM
LJP5
 72
hr
 765 3109 3148 0.9878 0.9879
Hs 578T Enzastaurin
3.33
uM
LJP5
 72
hr
 765 3135 3148 0.9958 0.9958
Hs 578T Enzastaurin
10
uM
LJP5
 72
hr
 765 3043 3148 0.9666 0.9670
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 765 2272 3101 0.7326 0.7144
Hs 578T Palbociclib
0.12
uM
LJP6
 72
hr
 765 1946 3101 0.6273 0.5875