LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T HG-5-88-01
10
uM
LJP6
 72
hr
 765 2098 3101 0.6765 0.6480
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 765 3471 3101 1.1194 1.1150
Hs 578T HG-6-64-01
0.12
uM
LJP6
 72
hr
 765 3351 3101 1.0806 1.0782
Hs 578T HG-6-64-01
0.37
uM
LJP6
 72
hr
 765 2937 3101 0.9467 0.9456
Hs 578T HG-6-64-01
1.11
uM
LJP6
 72
hr
 765 1522 3101 0.4905 0.4051
Hs 578T HG-6-64-01
3.33
uM
LJP6
 72
hr
 765 568 3101 0.1834 -0.1389
Hs 578T HG-6-64-01
10
uM
LJP6
 72
hr
 765 174 3101 0.0564 -0.5216
Hs 578T Neratinib
0.04
uM
LJP5
 72
hr
 765 2797 3148 0.8887 0.8876
Hs 578T Neratinib
0.12
uM
LJP5
 72
hr
 765 2591 3148 0.8232 0.8180
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 765 2248 3148 0.7143 0.6952
Hs 578T Neratinib
1.11
uM
LJP5
 72
hr
 765 2244 3148 0.7130 0.6939
Hs 578T Neratinib
3.33
uM
LJP5
 72
hr
 765 1654 3148 0.5255 0.4592
Hs 578T Neratinib
10
uM
LJP5
 72
hr
 765 1001 3148 0.3180 0.1380
Hs 578T JW-7-24-1
0.04
uM
LJP6
 72
hr
 765 2902 3101 0.9355 0.9348
Hs 578T JW-7-24-1
0.12
uM
LJP6
 72
hr
 765 2846 3101 0.9179 0.9169
Hs 578T JW-7-24-1
0.37
uM
LJP6
 72
hr
 765 2476 3101 0.7985 0.7891
Hs 578T JW-7-24-1
1.11
uM
LJP6
 72
hr
 765 1915 3101 0.6176 0.5753
Hs 578T JW-7-24-1
3.33
uM
LJP6
 72
hr
 765 1466 3101 0.4728 0.3800
Hs 578T JW-7-24-1
10
uM
LJP6
 72
hr
 765 414 3101 0.1335 -0.2622
Hs 578T Dasatinib
0.04
uM
LJP5
 72
hr
 765 1862 3148 0.5915 0.5462
Hs 578T Dasatinib
0.04
uM
LJP6
 72
hr
 765 1008 3101 0.3250 0.1452
Hs 578T Dasatinib
0.12
uM
LJP5
 72
hr
 765 1134 3148 0.3602 0.2125
Hs 578T Dasatinib
0.12
uM
LJP6
 72
hr
 765 531 3101 0.1711 -0.1664
Hs 578T Dasatinib
0.37
uM
LJP5
 72
hr
 765 524 3148 0.1667 -0.1690
Hs 578T Dasatinib
0.37
uM
LJP6
 72
hr
 765 509 3101 0.1641 -0.1829