LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Linsitinib
0.12
uM
LJP5
 72
hr
 1334 3722 4033 0.9226 0.9010
BT-20 Linsitinib
0.37
uM
LJP5
 72
hr
 1334 4078 4033 1.0121 1.0156
BT-20 Linsitinib
1.11
uM
LJP5
 72
hr
 1334 3950 4033 0.9796 0.9742
BT-20 Linsitinib
3.33
uM
LJP5
 72
hr
 1334 3836 4033 0.9519 0.9395
BT-20 Linsitinib
10
uM
LJP5
 72
hr
 1334 3535 4033 0.8769 0.8420
BT-20 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1334 4182 4033 1.0372 1.0465
BT-20 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1334 3911 4033 0.9699 0.9621
BT-20 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1334 4023 4033 0.9979 0.9978
BT-20 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1334 3996 4033 0.9903 0.9866
BT-20 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1334 3901 4033 0.9671 0.9581
BT-20 Ruxolitinib
10
uM
LJP5
 72
hr
 1334 3058 4033 0.7587 0.6823
BT-20 Momelotinib
0.04
uM
LJP5
 72
hr
 1334 3991 4033 0.9900 0.9877
BT-20 Momelotinib
0.12
uM
LJP5
 72
hr
 1334 3704 4033 0.9188 0.8969
BT-20 Momelotinib
0.37
uM
LJP5
 72
hr
 1334 3659 4033 0.9071 0.8811
BT-20 Momelotinib
1.11
uM
LJP5
 72
hr
 1334 3375 4033 0.8367 0.7878
BT-20 Momelotinib
3.33
uM
LJP5
 72
hr
 1334 2983 4033 0.7401 0.6562
BT-20 Momelotinib
10
uM
LJP5
 72
hr
 1334 1398 4033 0.3469 0.0293
BT-20 Fedratinib
0.04
uM
LJP5
 72
hr
 1334 4137 4033 1.0267 1.0338
BT-20 Fedratinib
0.12
uM
LJP5
 72
hr
 1334 3935 4033 0.9753 0.9679
BT-20 Fedratinib
0.37
uM
LJP5
 72
hr
 1334 3888 4033 0.9643 0.9550
BT-20 Fedratinib
1.11
uM
LJP5
 72
hr
 1334 3561 4033 0.8834 0.8506
BT-20 Fedratinib
3.33
uM
LJP5
 72
hr
 1334 2986 4033 0.7403 0.6561
BT-20 Fedratinib
10
uM
LJP5
 72
hr
 1334 842 4033 0.2086 -0.2519
BT-20 Trametinib
0.04
uM
LJP5
 72
hr
 1334 3155 4033 0.7821 0.7134
BT-20 Trametinib
0.12
uM
LJP5
 72
hr
 1334 3519 4033 0.8726 0.8361