LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset - HMS LINCS Database

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Small molecules	Cells

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Cell	Small Molecule	Small Mol Concentration	Small Mol Conc Unit	LJP Library Plate	Timepoint	Timepoint Unit	Mean Total Cell Count Before Treatment	Mean Total Cell Count After Treatment	Mean Total Control Cell Count	Mean Relative Cell Count	Mean Normalized Growth Rate Inhibition Value
BT-20	Trametinib	0.37	uM	LJP5	72	hr	1334	3392	4033	0.8408	0.7934
BT-20	Trametinib	1.11	uM	LJP5	72	hr	1334	3314	4033	0.8220	0.7689
BT-20	Trametinib	3.33	uM	LJP5	72	hr	1334	3106	4033	0.7703	0.6977
BT-20	Trametinib	10	uM	LJP5	72	hr	1334	3525	4033	0.8739	0.8375
BT-20	Omipalisib	0.04	uM	LJP6	72	hr	1334	1179	3925	0.3004	-0.0765
BT-20	Omipalisib	0.12	uM	LJP6	72	hr	1334	1045	3925	0.2664	-0.1453
BT-20	Omipalisib	0.37	uM	LJP6	72	hr	1334	856	3925	0.2181	-0.2484
BT-20	Omipalisib	1.11	uM	LJP6	72	hr	1334	734	3925	0.1869	-0.3208
BT-20	Omipalisib	3.33	uM	LJP6	72	hr	1334	566	3925	0.1441	-0.4249
BT-20	Omipalisib	10	uM	LJP6	72	hr	1334	479	3925	0.1221	-0.4825
BT-20	Buparlisib	0.04	uM	LJP5	72	hr	1334	4150	4033	1.0287	1.0355
BT-20	Buparlisib	0.12	uM	LJP5	72	hr	1334	3831	4033	0.9506	0.9379
BT-20	Buparlisib	0.37	uM	LJP5	72	hr	1334	2698	4033	0.6696	0.5555
BT-20	Buparlisib	1.11	uM	LJP5	72	hr	1334	1273	4033	0.3157	-0.0294
BT-20	Buparlisib	3.33	uM	LJP5	72	hr	1334	612	4033	0.1519	-0.3867
BT-20	Buparlisib	10	uM	LJP5	72	hr	1334	463	4033	0.1148	-0.4855
BT-20	XL147	0.04	uM	LJP5	72	hr	1334	4181	4033	1.0369	1.0462
BT-20	XL147	0.12	uM	LJP5	72	hr	1334	4014	4033	0.9957	0.9950
BT-20	XL147	0.37	uM	LJP5	72	hr	1334	3869	4033	0.9592	0.9483
BT-20	XL147	1.11	uM	LJP5	72	hr	1334	3794	4033	0.9412	0.9257
BT-20	XL147	3.33	uM	LJP5	72	hr	1334	3528	4033	0.8755	0.8400
BT-20	XL147	10	uM	LJP5	72	hr	1334	1451	4033	0.3602	0.0542
BT-20	Y39983	0.04	uM	LJP6	72	hr	1334	4097	3925	1.0434	1.0541
BT-20	Y39983	0.12	uM	LJP6	72	hr	1334	4299	3925	1.0950	1.1196
BT-20	Y39983	0.37	uM	LJP6	72	hr	1334	4100	3925	1.0444	1.0562

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HMS LINCS Project

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)