LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 PD184352
0.37
uM
LJP5
 72
hr
 1235 3401 4267 0.7967 0.7604
MCF7 PD184352
1.11
uM
LJP5
 72
hr
 1235 3287 4267 0.7703 0.7280
MCF7 PD184352
3.33
uM
LJP5
 72
hr
 1235 2897 4267 0.6791 0.6108
MCF7 PD184352
10
uM
LJP5
 72
hr
 1235 2074 4267 0.4856 0.3334
MCF7 PLX-4720
0.04
uM
LJP5
 72
hr
 1235 4683 4267 1.0972 1.1062
MCF7 PLX-4720
0.12
uM
LJP5
 72
hr
 1235 3969 4267 0.9288 0.9152
MCF7 PLX-4720
0.37
uM
LJP5
 72
hr
 1235 4133 4267 0.9681 0.9630
MCF7 PLX-4720
1.11
uM
LJP5
 72
hr
 1235 4186 4267 0.9820 0.9803
MCF7 PLX-4720
3.33
uM
LJP5
 72
hr
 1235 3327 4267 0.7799 0.7402
MCF7 PLX-4720
10
uM
LJP5
 72
hr
 1235 2141 4267 0.5032 0.3604
MCF7 Lapatinib
0.04
uM
LJP6
 72
hr
 1235 2964 4056 0.7319 0.6659
MCF7 Lapatinib
0.12
uM
LJP6
 72
hr
 1235 3265 4056 0.8057 0.7630
MCF7 Lapatinib
0.37
uM
LJP6
 72
hr
 1235 3706 4056 0.9130 0.8955
MCF7 Lapatinib
1.11
uM
LJP6
 72
hr
 1235 3799 4056 0.9368 0.9254
MCF7 Lapatinib
3.33
uM
LJP6
 72
hr
 1235 3964 4056 0.9764 0.9711
MCF7 Lapatinib
10
uM
LJP6
 72
hr
 1235 2264 4056 0.5585 0.4232
MCF7 Sirolimus
0.04
uM
LJP6
 72
hr
 1235 2655 4056 0.6541 0.5607
MCF7 Sirolimus
0.12
uM
LJP6
 72
hr
 1235 2650 4056 0.6532 0.5599
MCF7 Sirolimus
0.37
uM
LJP6
 72
hr
 1235 2499 4056 0.6160 0.5064
MCF7 Sirolimus
1.11
uM
LJP6
 72
hr
 1235 2650 4056 0.6531 0.5599
MCF7 Sirolimus
3.33
uM
LJP6
 72
hr
 1235 2532 4056 0.6242 0.5193
MCF7 Sirolimus
10
uM
LJP6
 72
hr
 1235 2605 4056 0.6421 0.5434
MCF7 ZSTK474
0.04
uM
LJP6
 72
hr
 1235 3330 4056 0.8218 0.7833
MCF7 ZSTK474
0.12
uM
LJP6
 72
hr
 1235 2292 4056 0.5656 0.4322
MCF7 ZSTK474
0.37
uM
LJP6
 72
hr
 1235 1566 4056 0.3863 0.1483