LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CGP60474 | 10 | uM | LJP6 | 72 | hr | 1235 | 383 | 4056 | 0.0945 | -0.4947 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4512 | 4056 | 1.1128 | 1.1288 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 4427 | 4056 | 1.0920 | 1.1053 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 4506 | 4056 | 1.1119 | 1.1274 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 4692 | 4056 | 1.1566 | 1.1765 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 4840 | 4056 | 1.1932 | 1.2169 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 72 | hr | 1235 | 3129 | 4056 | 0.7716 | 0.7187 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3325 | 4267 | 0.7794 | 0.7387 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3061 | 4267 | 0.7180 | 0.6618 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2485 | 4267 | 0.5824 | 0.4780 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1641 | 4267 | 0.3845 | 0.1715 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1243 | 4267 | 0.2913 | 0.0030 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 72 | hr | 1235 | 750 | 4267 | 0.1755 | -0.2447 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4482 | 4056 | 1.1046 | 1.1188 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 4307 | 4056 | 1.0614 | 1.0705 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 3766 | 4056 | 0.9291 | 0.9122 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2068 | 4056 | 0.5105 | 0.3498 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 975 | 4056 | 0.2404 | -0.1289 |
| MCF7 | BMS345541 | 10 | uM | LJP6 | 72 | hr | 1235 | 866 | 4056 | 0.2132 | -0.1885 |
| MCF7 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3928 | 4056 | 0.9685 | 0.9632 |
| MCF7 | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3752 | 4056 | 0.9264 | 0.9118 |
| MCF7 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 3856 | 4056 | 0.9506 | 0.9415 |
| MCF7 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3697 | 4056 | 0.9112 | 0.8944 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 3437 | 4056 | 0.8478 | 0.8164 |
| MCF7 | KIN001-043 | 10 | uM | LJP6 | 72 | hr | 1235 | 1765 | 4056 | 0.4350 | 0.2307 |