LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4146 | 4267 | 0.9704 | 0.9643 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4349 | 4267 | 1.0183 | 1.0191 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 72 | hr | 1235 | 1633 | 4267 | 0.3834 | 0.1690 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2761 | 4056 | 0.6810 | 0.5978 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2098 | 4056 | 0.5176 | 0.3621 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1370 | 4056 | 0.3378 | 0.0618 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1235 | 982 | 4056 | 0.2426 | -0.1256 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1064 | 4056 | 0.2624 | -0.0834 |
| MCF7 | JNK-9L | 10 | uM | LJP6 | 72 | hr | 1235 | 944 | 4056 | 0.2327 | -0.1453 |
| MCF7 | PD0325901 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 2959 | 4267 | 0.6937 | 0.6294 |
| MCF7 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2945 | 4056 | 0.7255 | 0.6577 |
| MCF7 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 2656 | 4267 | 0.6234 | 0.5354 |
| MCF7 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2490 | 4056 | 0.6132 | 0.5022 |
| MCF7 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2560 | 4267 | 0.5999 | 0.5021 |
| MCF7 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2320 | 4056 | 0.5725 | 0.4432 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2435 | 4267 | 0.5703 | 0.4603 |
| MCF7 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2251 | 4056 | 0.5550 | 0.4189 |
| MCF7 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1709 | 4267 | 0.4007 | 0.1987 |
| MCF7 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1593 | 4056 | 0.3926 | 0.1595 |
| MCF7 | PD0325901 | 10 | uM | LJP5 | 72 | hr | 1235 | 1168 | 4267 | 0.2739 | -0.0308 |
| MCF7 | PD0325901 | 10 | uM | LJP6 | 72 | hr | 1235 | 1104 | 4056 | 0.2724 | -0.0631 |
| MCF7 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1235 | 2274 | 4267 | 0.5332 | 0.4066 |
| MCF7 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2465 | 4056 | 0.6077 | 0.4953 |
| MCF7 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1560 | 4267 | 0.3652 | 0.1377 |
| MCF7 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1539 | 4056 | 0.3793 | 0.1365 |