LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1395 | 4267 | 0.3268 | 0.0695 |
| MCF7 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1321 | 4056 | 0.3257 | 0.0395 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1371 | 4267 | 0.3216 | 0.0600 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1452 | 4056 | 0.3576 | 0.0973 |
| MCF7 | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1297 | 4267 | 0.3044 | 0.0280 |
| MCF7 | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1242 | 4056 | 0.3059 | 0.0022 |
| MCF7 | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 1235 | 525 | 4267 | 0.1234 | -0.3802 |
| MCF7 | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 1235 | 552 | 4056 | 0.1361 | -0.3753 |
| MCF7 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4588 | 4267 | 1.0741 | 1.0800 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4254 | 4267 | 0.9964 | 0.9952 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 3881 | 4267 | 0.9098 | 0.8966 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2946 | 4267 | 0.6904 | 0.6255 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2289 | 4267 | 0.5366 | 0.4117 |
| MCF7 | YM 201636 | 10 | uM | LJP5 | 72 | hr | 1235 | 1809 | 4267 | 0.4241 | 0.2376 |
| MCF7 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4758 | 4267 | 1.1141 | 1.1229 |
| MCF7 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4177 | 4267 | 0.9810 | 0.9784 |
| MCF7 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4026 | 4267 | 0.9449 | 0.9377 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3874 | 4267 | 0.9080 | 0.8938 |
| MCF7 | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2631 | 4267 | 0.6170 | 0.5267 |
| MCF7 | TWS119 | 10 | uM | LJP5 | 72 | hr | 1235 | 731 | 4267 | 0.1716 | -0.2550 |
| MCF7 | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 2602 | 4267 | 0.6100 | 0.5168 |
| MCF7 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 2160 | 4267 | 0.5055 | 0.3640 |
| MCF7 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2037 | 4267 | 0.4773 | 0.3220 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1768 | 4267 | 0.4143 | 0.2213 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1674 | 4267 | 0.3922 | 0.1845 |