LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1114 | 4267 | 0.2615 | -0.0560 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1252 | 4267 | 0.2937 | 0.0076 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1167 | 4267 | 0.2735 | -0.0316 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 72 | hr | 1235 | 1103 | 4267 | 0.2581 | -0.0632 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1380 | 4267 | 0.3234 | 0.0624 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1170 | 4056 | 0.2884 | -0.0315 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1315 | 4267 | 0.3085 | 0.0356 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1156 | 4056 | 0.2850 | -0.0382 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1487 | 4267 | 0.3487 | 0.1092 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1296 | 4056 | 0.3199 | 0.0284 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1061 | 4267 | 0.2487 | -0.0817 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1235 | 988 | 4056 | 0.2437 | -0.1221 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1235 | 621 | 4267 | 0.1459 | -0.3190 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1235 | 660 | 4056 | 0.1627 | -0.3067 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 1235 | 420 | 4267 | 0.0987 | -0.4544 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 1235 | 408 | 4056 | 0.1006 | -0.4766 |
| MCF7 | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 1235 | 2719 | 4267 | 0.6374 | 0.5521 |
| MCF7 | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2568 | 4056 | 0.6331 | 0.5319 |
| MCF7 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1760 | 4267 | 0.4129 | 0.2192 |
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1793 | 4056 | 0.4424 | 0.2429 |
| MCF7 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1603 | 4267 | 0.3757 | 0.1566 |
| MCF7 | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1601 | 4056 | 0.3950 | 0.1633 |
| MCF7 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1587 | 4267 | 0.3717 | 0.1496 |
| MCF7 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1626 | 4056 | 0.4010 | 0.1737 |
| MCF7 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1664 | 4267 | 0.3900 | 0.1808 |