LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1503 | 4056 | 0.3710 | 0.1215 |
| MCF7 | Radicicol | 10 | uM | LJP5 | 72 | hr | 1235 | 998 | 4267 | 0.2342 | -0.1122 |
| MCF7 | Radicicol | 10 | uM | LJP6 | 72 | hr | 1235 | 947 | 4056 | 0.2338 | -0.1433 |
| MCF7 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4676 | 4267 | 1.0974 | 1.1073 |
| MCF7 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3891 | 4056 | 0.9585 | 0.9496 |
| MCF7 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3865 | 4267 | 0.9062 | 0.8923 |
| MCF7 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3365 | 4056 | 0.8288 | 0.7911 |
| MCF7 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1871 | 4267 | 0.4386 | 0.2603 |
| MCF7 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1735 | 4056 | 0.4279 | 0.2191 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1563 | 4267 | 0.3666 | 0.1408 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1337 | 4056 | 0.3297 | 0.0471 |
| MCF7 | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1035 | 4267 | 0.2429 | -0.0941 |
| MCF7 | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1051 | 4056 | 0.2589 | -0.0908 |
| MCF7 | Withaferin A | 10 | uM | LJP5 | 72 | hr | 1235 | 1111 | 4267 | 0.2599 | -0.0602 |
| MCF7 | Withaferin A | 10 | uM | LJP6 | 72 | hr | 1235 | 1032 | 4056 | 0.2547 | -0.0992 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4165 | 3772 | 1.1039 | 1.1507 |
| SK-BR-3 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4001 | 3772 | 1.0607 | 1.0888 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3951 | 3772 | 1.0473 | 1.0692 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3292 | 3772 | 0.8728 | 0.8087 |
| SK-BR-3 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2912 | 3772 | 0.7723 | 0.6524 |
| SK-BR-3 | Seliciclib | 10 | uM | LJP5 | 72 | hr | 1476 | 1413 | 3772 | 0.3745 | -0.0323 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3146 | 3643 | 0.8668 | 0.7950 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1759 | 3643 | 0.4832 | 0.1428 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1424 | 3643 | 0.3915 | -0.0279 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1152 | 3643 | 0.3175 | -0.1732 |