LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Saracatinib
0.04
uM
LJP6
 72
hr
 1235 3767 4056 0.9293 0.9157
MCF7 Saracatinib
0.12
uM
LJP6
 72
hr
 1235 2857 4056 0.7050 0.6295
MCF7 Saracatinib
0.37
uM
LJP6
 72
hr
 1235 2013 4056 0.4969 0.3296
MCF7 Saracatinib
1.11
uM
LJP6
 72
hr
 1235 1688 4056 0.4160 0.1981
MCF7 Saracatinib
3.33
uM
LJP6
 72
hr
 1235 1502 4056 0.3702 0.1204
MCF7 Saracatinib
10
uM
LJP6
 72
hr
 1235 1703 4056 0.4198 0.2044
MCF7 Sigma A6730
0.04
uM
LJP5
 72
hr
 1235 3330 4267 0.7796 0.7379
MCF7 Sigma A6730
0.12
uM
LJP5
 72
hr
 1235 3215 4267 0.7537 0.7076
MCF7 Sigma A6730
0.37
uM
LJP5
 72
hr
 1235 3167 4267 0.7430 0.6937
MCF7 Sigma A6730
1.11
uM
LJP5
 72
hr
 1235 2317 4267 0.5436 0.4221
MCF7 Sigma A6730
3.33
uM
LJP5
 72
hr
 1235 2373 4267 0.5560 0.4399
MCF7 Sigma A6730
10
uM
LJP5
 72
hr
 1235 1211 4267 0.2839 -0.0120
MCF7 WH-4-025
0.04
uM
LJP5
 72
hr
 1235 4203 4267 0.9846 0.9821
MCF7 WH-4-025
0.12
uM
LJP5
 72
hr
 1235 2787 4267 0.6530 0.5752
MCF7 WH-4-025
0.37
uM
LJP5
 72
hr
 1235 1967 4267 0.4616 0.2978
MCF7 WH-4-025
1.11
uM
LJP5
 72
hr
 1235 1226 4267 0.2866 -0.0076
MCF7 WH-4-025
3.33
uM
LJP5
 72
hr
 1235 1388 4267 0.3259 0.0678
MCF7 WH-4-025
10
uM
LJP5
 72
hr
 1235 1043 4267 0.2445 -0.0907
MCF7 R406
0.04
uM
LJP6
 72
hr
 1235 4106 4056 1.0121 1.0134
MCF7 R406
0.12
uM
LJP6
 72
hr
 1235 4432 4056 1.0921 1.1050
MCF7 R406
0.37
uM
LJP6
 72
hr
 1235 3615 4056 0.8913 0.8702
MCF7 R406
1.11
uM
LJP6
 72
hr
 1235 3733 4056 0.9203 0.9053
MCF7 R406
3.33
uM
LJP6
 72
hr
 1235 3054 4056 0.7535 0.6956
MCF7 R406
10
uM
LJP6
 72
hr
 1235 1756 4056 0.4329 0.2272
MCF7 BI-2536
0.04
uM
LJP6
 72
hr
 1235 1523 4056 0.3753 0.1294