LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1433 | 4267 | 0.3365 | 0.0872 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 72 | hr | 1235 | 1318 | 4267 | 0.3093 | 0.0369 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4481 | 4056 | 1.1045 | 1.1187 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 4463 | 4056 | 1.1009 | 1.1145 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 4629 | 4056 | 1.1420 | 1.1596 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 4431 | 4056 | 1.0919 | 1.1043 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 4335 | 4056 | 1.0693 | 1.0789 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 72 | hr | 1235 | 3826 | 4056 | 0.9431 | 0.9310 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2633 | 4056 | 0.6499 | 0.5548 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1410 | 4056 | 0.3478 | 0.0803 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1196 | 4056 | 0.2949 | -0.0187 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1065 | 4056 | 0.2630 | -0.0834 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1021 | 4056 | 0.2515 | -0.1058 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 72 | hr | 1235 | 1168 | 4056 | 0.2881 | -0.0319 |
| MCF7 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4211 | 4267 | 0.9887 | 0.9876 |
| MCF7 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 604 | 4056 | 0.1487 | -0.3425 |
| MCF7 | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 774 | 4267 | 0.1812 | -0.2311 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 587 | 4056 | 0.1448 | -0.3520 |
| MCF7 | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 777 | 4267 | 0.1822 | -0.2286 |
| MCF7 | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 592 | 4056 | 0.1461 | -0.3491 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 861 | 4267 | 0.2024 | -0.1851 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 551 | 4056 | 0.1358 | -0.3756 |
| MCF7 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 673 | 4267 | 0.1576 | -0.2896 |
| MCF7 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 514 | 4056 | 0.1269 | -0.4009 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 72 | hr | 1235 | 670 | 4267 | 0.1573 | -0.2899 |