LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 2
E24
 72
hr
 1235 4295 4578 0.9381 0.9335
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 1235 5042 4929 1.0229 1.0228
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 1235 3783 4474 0.8454 0.8270
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 1235 3726 4578 0.8138 0.7934
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 1235 4228 4929 0.8577 0.8520
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 1235 2297 4474 0.5133 0.3964
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 1235 2404 4578 0.5251 0.4221
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 1235 3106 4929 0.6301 0.5868
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 1235 2108 4474 0.4711 0.3333
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 1235 2006 4578 0.4381 0.2922
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 1235 2440 4929 0.4950 0.4061
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 1235 1860 4474 0.4157 0.2463
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 1235 1959 4578 0.4279 0.2761
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 1235 1997 4929 0.4051 0.2718
MDA-MB-231 Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 1235 1480 4474 0.3308 0.1020
MDA-MB-231 Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 1235 1479 4578 0.3230 0.0997
MDA-MB-231 Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 1235 1686 4929 0.3420 0.1684
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 1235 3905 4474 0.8727 0.8585
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 1235 3952 4578 0.8632 0.8501
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 1235 4626 4929 0.9385 0.9374
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 1235 3967 4474 0.8865 0.8744
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 2
F23
 72
hr
 1235 4100 4578 0.8955 0.8865
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 3
F23
 72
hr
 1235 4616 4929 0.9364 0.9353
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 1
F22
 72
hr
 1235 4053 4474 0.9058 0.8961
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 2
F22
 72
hr
 1235 4214 4578 0.9204 0.9141