LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PHA-665752
3.33
uM
LJP5
 1
F14
 72
hr
 1235 4302 4474 0.9614 0.9580
MDA-MB-231 PHA-665752
3.33
uM
LJP5
 2
F14
 72
hr
 1235 4359 4578 0.9520 0.9487
MDA-MB-231 PHA-665752
3.33
uM
LJP5
 3
F14
 72
hr
 1235 4370 4929 0.8865 0.8829
MDA-MB-231 PHA-665752
10
uM
LJP5
 1
F13
 72
hr
 1235 133 4474 0.0297 -0.6991
MDA-MB-231 PHA-665752
10
uM
LJP5
 2
F13
 72
hr
 1235 130 4578 0.0284 -0.6964
MDA-MB-231 PHA-665752
10
uM
LJP5
 3
F13
 72
hr
 1235 131 4929 0.0266 -0.6752
MDA-MB-231 PI103
0.04
uM
LJP6
 1
I18
 72
hr
 1235 3102 4355 0.7121 0.6592
MDA-MB-231 PI103
0.04
uM
LJP6
 2
I18
 72
hr
 1235 3274 4277 0.7654 0.7227
MDA-MB-231 PI103
0.04
uM
LJP6
 3
I18
 72
hr
 1235 3292 4583 0.7183 0.6789
MDA-MB-231 PI103
0.12
uM
LJP6
 1
I17
 72
hr
 1235 2594 4355 0.5955 0.5037
MDA-MB-231 PI103
0.12
uM
LJP6
 2
I17
 72
hr
 1235 2710 4277 0.6336 0.5501
MDA-MB-231 PI103
0.12
uM
LJP6
 3
I17
 72
hr
 1235 2701 4583 0.5893 0.5121
MDA-MB-231 PI103
0.37
uM
LJP6
 1
I16
 72
hr
 1235 2016 4355 0.4628 0.3090
MDA-MB-231 PI103
0.37
uM
LJP6
 2
I16
 72
hr
 1235 2228 4277 0.5209 0.3896
MDA-MB-231 PI103
0.37
uM
LJP6
 3
I16
 72
hr
 1235 608 4583 0.1327 -0.3129
MDA-MB-231 PI103
1.11
uM
LJP6
 1
I15
 72
hr
 1235 1689 4355 0.3878 0.1875
MDA-MB-231 PI103
1.11
uM
LJP6
 2
I15
 72
hr
 1235 2008 4277 0.4695 0.3112
MDA-MB-231 PI103
1.11
uM
LJP6
 3
I15
 72
hr
 1235 1809 4583 0.3947 0.2232
MDA-MB-231 PI103
3.33
uM
LJP6
 1
I14
 72
hr
 1235 1471 4355 0.3377 0.1005
MDA-MB-231 PI103
3.33
uM
LJP6
 2
I14
 72
hr
 1235 1753 4277 0.4098 0.2155
MDA-MB-231 PI103
3.33
uM
LJP6
 3
I14
 72
hr
 1235 1612 4583 0.3517 0.1508
MDA-MB-231 PI103
10
uM
LJP6
 1
I13
 72
hr
 1235 1065 4355 0.2445 -0.0786
MDA-MB-231 PI103
10
uM
LJP6
 2
I13
 72
hr
 1235 1154 4277 0.2698 -0.0376
MDA-MB-231 PI103
10
uM
LJP6
 3
I13
 72
hr
 1235 1198 4583 0.2614 -0.0164
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 1
E24
 72
hr
 1235 4345 4474 0.9710 0.9686