LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 3
E17
 72
hr
 1235 4890 4929 0.9920 0.9920
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 1
E16
 72
hr
 1235 4645 4474 1.0381 1.0407
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 2
E16
 72
hr
 1235 4644 4578 1.0143 1.0151
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 3
E16
 72
hr
 1235 4522 4929 0.9174 0.9154
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 1
E15
 72
hr
 1235 4328 4474 0.9672 0.9644
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 2
E15
 72
hr
 1235 4817 4578 1.0521 1.0545
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 3
E15
 72
hr
 1235 4731 4929 0.9598 0.9593
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 1
E14
 72
hr
 1235 4211 4474 0.9411 0.9356
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 2
E14
 72
hr
 1235 4585 4578 1.0014 1.0015
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 3
E14
 72
hr
 1235 4672 4929 0.9478 0.9470
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 1
E13
 72
hr
 1235 1014 4474 0.2266 -0.1012
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 2
E13
 72
hr
 1235 1162 4578 0.2538 -0.0321
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 3
E13
 72
hr
 1235 1873 4929 0.3800 0.2316
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 1
F18
 72
hr
 1235 4771 4474 1.0662 1.0703
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 2
F18
 72
hr
 1235 4971 4578 1.0857 1.0890
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 3
F18
 72
hr
 1235 4963 4929 1.0068 1.0068
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 1
F17
 72
hr
 1235 4596 4474 1.0271 1.0290
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 2
F17
 72
hr
 1235 4617 4578 1.0084 1.0089
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 3
F17
 72
hr
 1235 4766 4929 0.9669 0.9665
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 1
F16
 72
hr
 1235 4579 4474 1.0233 1.0250
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 2
F16
 72
hr
 1235 4578 4578 0.9999 0.9999
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 3
F16
 72
hr
 1235 5001 4929 1.0145 1.0145
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 1
F15
 72
hr
 1235 4604 4474 1.0289 1.0309
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 2
F15
 72
hr
 1235 4695 4578 1.0254 1.0268
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 3
F15
 72
hr
 1235 4636 4929 0.9405 0.9395