LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SU11274
10
uM
LJP5
 2
J07
 72
hr
 1235 1118 4578 0.2442 -0.0517
MDA-MB-231 SU11274
10
uM
LJP5
 3
J07
 72
hr
 1235 1255 4929 0.2546 0.0077
MDA-MB-231 Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 1235 4449 4355 1.0214 1.0234
MDA-MB-231 Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 1235 4340 4277 1.0146 1.0163
MDA-MB-231 Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 1235 4607 4583 1.0052 1.0054
MDA-MB-231 Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 1235 4261 4355 0.9782 0.9759
MDA-MB-231 Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 1235 4138 4277 0.9674 0.9634
MDA-MB-231 Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 1235 4569 4583 0.9969 0.9967
MDA-MB-231 Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 1235 3973 4355 0.9121 0.9013
MDA-MB-231 Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 1235 3836 4277 0.8968 0.8820
MDA-MB-231 Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 1235 4262 4583 0.9299 0.9246
MDA-MB-231 Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 1235 3416 4355 0.7842 0.7496
MDA-MB-231 Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 1235 3252 4277 0.7603 0.7162
MDA-MB-231 Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 1235 3672 4583 0.8012 0.7787
MDA-MB-231 Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 1235 2419 4355 0.5553 0.4470
MDA-MB-231 Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 1235 2600 4277 0.6079 0.5147
MDA-MB-231 Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 1235 2386 4583 0.5206 0.4161
MDA-MB-231 Canertinib
10
uM
LJP6
 1
H07
 72
hr
 1235 620 4355 0.1423 -0.3159
MDA-MB-231 Canertinib
10
uM
LJP6
 2
H07
 72
hr
 1235 560 4277 0.1309 -0.3573
MDA-MB-231 Canertinib
10
uM
LJP6
 3
H07
 72
hr
 1235 727 4583 0.1586 -0.2447
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 1235 4753 4474 1.0622 1.0661
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 1235 4896 4578 1.0693 1.0722
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 1235 4786 4929 0.9709 0.9707
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 1235 4737 4474 1.0586 1.0623
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 2
E17
 72
hr
 1235 4776 4578 1.0431 1.0452