LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 1235 4233 4474 0.9460 0.9411
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 1235 4256 4578 0.9296 0.9241
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 1235 4883 4929 0.9906 0.9906
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 1235 3610 4474 0.8068 0.7815
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 1235 3889 4578 0.8494 0.8345
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 1235 4464 4929 0.9056 0.9031
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 1
H03
 72
hr
 1235 2542 4474 0.5681 0.4748
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 2
H03
 72
hr
 1235 2780 4578 0.6072 0.5358
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 3
H03
 72
hr
 1235 3407 4929 0.6912 0.6621
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 1235 1262 4474 0.2820 0.0113
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 1235 1207 4578 0.2636 -0.0125
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 1235 1582 4929 0.3209 0.1317
MDA-MB-231 Buparlisib
10
uM
LJP5
 1
H01
 72
hr
 1235 506 4474 0.1131 -0.3819
MDA-MB-231 Buparlisib
10
uM
LJP5
 2
H01
 72
hr
 1235 390 4578 0.0852 -0.4569
MDA-MB-231 Buparlisib
10
uM
LJP5
 3
H01
 72
hr
 1235 624 4929 0.1266 -0.2900
MDA-MB-231 XL147
0.04
uM
LJP5
 1
G12
 72
hr
 1235 4858 4474 1.0857 1.0905
MDA-MB-231 XL147
0.04
uM
LJP5
 2
G12
 72
hr
 1235 4938 4578 1.0785 1.0816
MDA-MB-231 XL147
0.04
uM
LJP5
 3
G12
 72
hr
 1235 5260 4929 1.0671 1.0661
MDA-MB-231 XL147
0.12
uM
LJP5
 1
G11
 72
hr
 1235 4743 4474 1.0600 1.0637
MDA-MB-231 XL147
0.12
uM
LJP5
 2
G11
 72
hr
 1235 5217 4578 1.1394 1.1431
MDA-MB-231 XL147
0.12
uM
LJP5
 3
G11
 72
hr
 1235 4926 4929 0.9993 0.9993
MDA-MB-231 XL147
0.37
uM
LJP5
 1
G10
 72
hr
 1235 4748 4474 1.0611 1.0649
MDA-MB-231 XL147
0.37
uM
LJP5
 2
G10
 72
hr
 1235 5019 4578 1.0962 1.0996
MDA-MB-231 XL147
0.37
uM
LJP5
 3
G10
 72
hr
 1235 4699 4929 0.9533 0.9526
MDA-MB-231 XL147
1.11
uM
LJP5
 1
G09
 72
hr
 1235 4927 4474 1.1011 1.1065