LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 3
F22
 72
hr
 1235 4773 4929 0.9683 0.9680
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 1
F21
 72
hr
 1235 4126 4474 0.9221 0.9145
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 2
F21
 72
hr
 1235 4516 4578 0.9863 0.9855
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 3
F21
 72
hr
 1235 4931 4929 1.0003 1.0003
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 1
F20
 72
hr
 1235 4584 4474 1.0244 1.0262
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 2
F20
 72
hr
 1235 4848 4578 1.0588 1.0615
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 3
F20
 72
hr
 1235 5038 4929 1.0221 1.0220
MDA-MB-231 GSK 690693
10
uM
LJP5
 1
F19
 72
hr
 1235 3477 4474 0.7770 0.7458
MDA-MB-231 GSK 690693
10
uM
LJP5
 2
F19
 72
hr
 1235 3788 4578 0.8273 0.8091
MDA-MB-231 GSK 690693
10
uM
LJP5
 3
F19
 72
hr
 1235 3890 4929 0.7892 0.7763
MDA-MB-231 SNS-032
0.04
uM
LJP6
 1
H18
 72
hr
 1235 2186 4355 0.5018 0.3686
MDA-MB-231 SNS-032
0.04
uM
LJP6
 2
H18
 72
hr
 1235 2040 4277 0.4769 0.3228
MDA-MB-231 SNS-032
0.04
uM
LJP6
 3
H18
 72
hr
 1235 2643 4583 0.5767 0.4948
MDA-MB-231 SNS-032
0.12
uM
LJP6
 1
H17
 72
hr
 1235 574 4355 0.1318 -0.3443
MDA-MB-231 SNS-032
0.12
uM
LJP6
 2
H17
 72
hr
 1235 555 4277 0.1298 -0.3605
MDA-MB-231 SNS-032
0.12
uM
LJP6
 3
H17
 72
hr
 1235 533 4583 0.1163 -0.3591
MDA-MB-231 SNS-032
0.37
uM
LJP6
 1
H16
 72
hr
 1235 462 4355 0.1061 -0.4181
MDA-MB-231 SNS-032
0.37
uM
LJP6
 2
H16
 72
hr
 1235 468 4277 0.1094 -0.4185
MDA-MB-231 SNS-032
0.37
uM
LJP6
 3
H16
 72
hr
 1235 537 4583 0.1172 -0.3565
MDA-MB-231 SNS-032
1.11
uM
LJP6
 1
H15
 72
hr
 1235 582 4355 0.1336 -0.3393
MDA-MB-231 SNS-032
1.11
uM
LJP6
 2
H15
 72
hr
 1235 470 4277 0.1099 -0.4172
MDA-MB-231 SNS-032
1.11
uM
LJP6
 3
H15
 72
hr
 1235 525 4583 0.1145 -0.3642
MDA-MB-231 SNS-032
3.33
uM
LJP6
 1
H14
 72
hr
 1235 579 4355 0.1329 -0.3412
MDA-MB-231 SNS-032
3.33
uM
LJP6
 2
H14
 72
hr
 1235 469 4277 0.1097 -0.4178
MDA-MB-231 SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 1235 542 4583 0.1183 -0.3534