LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Foretinib
0.37
uM
LJP5
 1
H10
 72
hr
 1235 1296 4474 0.2896 0.0259
MDA-MB-231 Foretinib
0.37
uM
LJP5
 2
H10
 72
hr
 1235 1365 4578 0.2981 0.0540
MDA-MB-231 Foretinib
0.37
uM
LJP5
 3
H10
 72
hr
 1235 1508 4929 0.3059 0.1048
MDA-MB-231 Foretinib
1.11
uM
LJP5
 1
H09
 72
hr
 1235 1406 4474 0.3142 0.0719
MDA-MB-231 Foretinib
1.11
uM
LJP5
 2
H09
 72
hr
 1235 1223 4578 0.2671 -0.0056
MDA-MB-231 Foretinib
1.11
uM
LJP5
 3
H09
 72
hr
 1235 1485 4929 0.3013 0.0963
MDA-MB-231 Foretinib
3.33
uM
LJP5
 1
H08
 72
hr
 1235 1073 4474 0.2398 -0.0733
MDA-MB-231 Foretinib
3.33
uM
LJP5
 2
H08
 72
hr
 1235 1157 4578 0.2527 -0.0343
MDA-MB-231 Foretinib
3.33
uM
LJP5
 3
H08
 72
hr
 1235 1137 4929 0.2307 -0.0410
MDA-MB-231 Foretinib
10
uM
LJP5
 1
H07
 72
hr
 1235 633 4474 0.1415 -0.3027
MDA-MB-231 Foretinib
10
uM
LJP5
 2
H07
 72
hr
 1235 712 4578 0.1555 -0.2532
MDA-MB-231 Foretinib
10
uM
LJP5
 3
H07
 72
hr
 1235 780 4929 0.1582 -0.2060
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 1
J06
 72
hr
 1235 3482 4355 0.7994 0.7681
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 2
J06
 72
hr
 1235 3297 4277 0.7708 0.7295
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 3
J06
 72
hr
 1235 3449 4583 0.7525 0.7208
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 1
J05
 72
hr
 1235 2837 4355 0.6513 0.5797
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 2
J05
 72
hr
 1235 2826 4277 0.6607 0.5868
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 3
J05
 72
hr
 1235 2683 4583 0.5854 0.5067
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 1
J04
 72
hr
 1235 1783 4355 0.4093 0.2234
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 2
J04
 72
hr
 1235 1814 4277 0.4241 0.2389
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 3
J04
 72
hr
 1235 1838 4583 0.4010 0.2335
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 1
J03
 72
hr
 1235 913 4355 0.2096 -0.1535
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 2
J03
 72
hr
 1235 1026 4277 0.2399 -0.0987
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 3
J03
 72
hr
 1235 935 4583 0.2040 -0.1372
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 1
J02
 72
hr
 1235 533 4355 0.1224 -0.3705