LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Y39983
10
uM
LJP6
 3
P01
 72
hr
 1235 373 4583 0.0814 -0.4693
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 1235 4957 4355 1.1380 1.1474
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 1235 4735 4277 1.1070 1.1168
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 1235 4843 4583 1.0566 1.0591
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 1235 4813 4355 1.1049 1.1129
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 1235 4675 4277 1.0930 1.1018
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 1235 4488 4583 0.9792 0.9779
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 1
H04
 72
hr
 1235 4482 4355 1.0289 1.0316
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 2
H04
 72
hr
 1235 4134 4277 0.9665 0.9623
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 3
H04
 72
hr
 1235 4617 4583 1.0073 1.0078
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 1
H03
 72
hr
 1235 4302 4355 0.9876 0.9863
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 2
H03
 72
hr
 1235 4295 4277 1.0041 1.0046
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 3
H03
 72
hr
 1235 4250 4583 0.9273 0.9217
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 1235 4062 4355 0.9325 0.9246
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 1235 4082 4277 0.9543 0.9485
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 1235 4093 4583 0.8930 0.8838
MDA-MB-231 Nintedanib
10
uM
LJP6
 1
H01
 72
hr
 1235 803 4355 0.1844 -0.2112
MDA-MB-231 Nintedanib
10
uM
LJP6
 2
H01
 72
hr
 1235 945 4277 0.2209 -0.1392
MDA-MB-231 Nintedanib
10
uM
LJP6
 3
H01
 72
hr
 1235 1551 4583 0.3384 0.1276
MDA-MB-231 Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 1235 4050 4474 0.9051 0.8954
MDA-MB-231 Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 1235 4231 4578 0.9241 0.9182
MDA-MB-231 Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 1235 4518 4929 0.9166 0.9146
MDA-MB-231 Foretinib
0.12
uM
LJP5
 1
H11
 72
hr
 1235 2735 4474 0.6112 0.5341
MDA-MB-231 Foretinib
0.12
uM
LJP5
 2
H11
 72
hr
 1235 3249 4578 0.7096 0.6679
MDA-MB-231 Foretinib
0.12
uM
LJP5
 3
H11
 72
hr
 1235 3261 4929 0.6616 0.6260