LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SNS-032
10
uM
LJP6
 1
H13
 72
hr
 1235 549 4355 0.1260 -0.3602
MDA-MB-231 SNS-032
10
uM
LJP6
 2
H13
 72
hr
 1235 606 4277 0.1417 -0.3283
MDA-MB-231 SNS-032
10
uM
LJP6
 3
H13
 72
hr
 1235 616 4583 0.1344 -0.3081
MDA-MB-231 Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 1235 3848 4355 0.8834 0.8681
MDA-MB-231 Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 1235 4336 4277 1.0137 1.0153
MDA-MB-231 Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 1235 4579 4583 0.9991 0.9990
MDA-MB-231 Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 1235 4191 4355 0.9621 0.9580
MDA-MB-231 Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 1235 3858 4277 0.9020 0.8880
MDA-MB-231 Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 1235 4187 4583 0.9135 0.9066
MDA-MB-231 Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 1235 3577 4355 0.8212 0.7945
MDA-MB-231 Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 1235 3623 4277 0.8470 0.8229
MDA-MB-231 Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 1235 3533 4583 0.7708 0.7428
MDA-MB-231 Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 1235 2814 4355 0.6460 0.5726
MDA-MB-231 Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 1235 2709 4277 0.6333 0.5498
MDA-MB-231 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 1235 2695 4583 0.5880 0.5103
MDA-MB-231 Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 1235 2684 4355 0.6162 0.5322
MDA-MB-231 Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 1235 2714 4277 0.6345 0.5514
MDA-MB-231 Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 1235 2849 4583 0.6216 0.5553
MDA-MB-231 Afatinib
10
uM
LJP6
 1
G19
 72
hr
 1235 577 4355 0.1325 -0.3424
MDA-MB-231 Afatinib
10
uM
LJP6
 2
G19
 72
hr
 1235 647 4277 0.1513 -0.3033
MDA-MB-231 Afatinib
10
uM
LJP6
 3
G19
 72
hr
 1235 662 4583 0.1444 -0.2812
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 1235 3805 4355 0.8735 0.8566
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 1235 3985 4277 0.9317 0.9225
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 3
H24
 72
hr
 1235 4082 4583 0.8906 0.8811
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 1
H23
 72
hr
 1235 3953 4355 0.9075 0.8960