LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | PD0325901 | 1.11 | uM | LJP5 | 1 | C03 | 72 | hr | 1235 | 1289 | 4474 | 0.2881 | 0.0229 |
| MDA-MB-231 | PD0325901 | 1.11 | uM | LJP5 | 2 | C03 | 72 | hr | 1235 | 1204 | 4578 | 0.2630 | -0.0138 |
| MDA-MB-231 | PD0325901 | 1.11 | uM | LJP5 | 3 | C03 | 72 | hr | 1235 | 1392 | 4929 | 0.2824 | 0.0614 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP6 | 1 | E02 | 72 | hr | 1235 | 720 | 4355 | 0.1653 | -0.2572 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP6 | 2 | E02 | 72 | hr | 1235 | 378 | 4277 | 0.0884 | -0.4839 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP6 | 3 | E02 | 72 | hr | 1235 | 1109 | 4583 | 0.2420 | -0.0557 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP5 | 1 | C02 | 72 | hr | 1235 | 1059 | 4474 | 0.2367 | -0.0799 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP5 | 2 | C02 | 72 | hr | 1235 | 955 | 4578 | 0.2086 | -0.1276 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP5 | 3 | C02 | 72 | hr | 1235 | 1089 | 4929 | 0.2209 | -0.0615 |
| MDA-MB-231 | PD0325901 | 10 | uM | LJP6 | 1 | E01 | 72 | hr | 1235 | 595 | 4355 | 0.1366 | -0.3312 |
| MDA-MB-231 | PD0325901 | 10 | uM | LJP6 | 2 | E01 | 72 | hr | 1235 | 300 | 4277 | 0.0701 | -0.5464 |
| MDA-MB-231 | PD0325901 | 10 | uM | LJP6 | 3 | E01 | 72 | hr | 1235 | 1030 | 4583 | 0.2247 | -0.0919 |
| MDA-MB-231 | PD0325901 | 10 | uM | LJP5 | 1 | C01 | 72 | hr | 1235 | 827 | 4474 | 0.1848 | -0.1946 |
| MDA-MB-231 | PD0325901 | 10 | uM | LJP5 | 2 | C01 | 72 | hr | 1235 | 639 | 4578 | 0.1396 | -0.2947 |
| MDA-MB-231 | PD0325901 | 10 | uM | LJP5 | 3 | C01 | 72 | hr | 1235 | 1041 | 4929 | 0.2112 | -0.0824 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP6 | 1 | O06 | 72 | hr | 1235 | 1962 | 4355 | 0.4504 | 0.2895 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP6 | 2 | O06 | 72 | hr | 1235 | 1191 | 4277 | 0.2784 | -0.0205 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP6 | 3 | O06 | 72 | hr | 1235 | 2476 | 4583 | 0.5402 | 0.4441 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP5 | 1 | O06 | 72 | hr | 1235 | 2309 | 4474 | 0.5160 | 0.4003 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP5 | 2 | O06 | 72 | hr | 1235 | 2310 | 4578 | 0.5045 | 0.3924 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP5 | 3 | O06 | 72 | hr | 1235 | 3131 | 4929 | 0.6352 | 0.5932 |
| MDA-MB-231 | Geldanamycin | 0.12 | uM | LJP6 | 1 | O05 | 72 | hr | 1235 | 1146 | 4355 | 0.2631 | -0.0407 |
| MDA-MB-231 | Geldanamycin | 0.12 | uM | LJP6 | 2 | O05 | 72 | hr | 1235 | 979 | 4277 | 0.2289 | -0.1220 |
| MDA-MB-231 | Geldanamycin | 0.12 | uM | LJP6 | 3 | O05 | 72 | hr | 1235 | 1178 | 4583 | 0.2570 | -0.0251 |
| MDA-MB-231 | Geldanamycin | 0.12 | uM | LJP5 | 1 | O05 | 72 | hr | 1235 | 1045 | 4474 | 0.2335 | -0.0864 |