LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SU11274
3.33
uM
LJP5
 2
J08
 72
hr
 513 5668 10349 0.5477 0.7406
MCF 10A SU11274
3.33
uM
LJP5
 3
J08
 72
hr
 513 5187 10483 0.4948 0.7014
MCF 10A SU11274
10
uM
LJP5
 1
J07
 72
hr
 513 2723 10254 0.2655 0.4714
MCF 10A SU11274
10
uM
LJP5
 2
J07
 72
hr
 513 2592 10349 0.2505 0.4530
MCF 10A SU11274
10
uM
LJP5
 3
J07
 72
hr
 513 2491 10483 0.2376 0.4375
MCF 10A Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 513 2926 10537 0.2777 0.4907
MCF 10A Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 513 1976 10386 0.1902 0.3643
MCF 10A Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 513 2332 10494 0.2222 0.4157
MCF 10A Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 513 1139 10537 0.1081 0.2006
MCF 10A Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 513 985 10386 0.0948 0.1621
MCF 10A Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 513 1237 10494 0.1179 0.2239
MCF 10A Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 513 801 10537 0.0760 0.1074
MCF 10A Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 513 668 10386 0.0643 0.0626
MCF 10A Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 513 742 10494 0.0707 0.0883
MCF 10A Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 513 675 10537 0.0641 0.0648
MCF 10A Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 513 651 10386 0.0627 0.0563
MCF 10A Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 513 663 10494 0.0632 0.0605
MCF 10A Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 513 761 10537 0.0722 0.0945
MCF 10A Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 513 680 10386 0.0655 0.0669
MCF 10A Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 513 642 10494 0.0612 0.0527
MCF 10A Canertinib
10
uM
LJP6
 1
H07
 72
hr
 513 350 10537 0.0332 -0.0841
MCF 10A Canertinib
10
uM
LJP6
 2
H07
 72
hr
 513 158 10386 0.0152 -0.2378
MCF 10A Canertinib
10
uM
LJP6
 3
H07
 72
hr
 513 162 10494 0.0154 -0.2327
MCF 10A NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 513 9554 10254 0.9317 0.9675
MCF 10A NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 513 9671 10349 0.9344 0.9690