LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | Seliciclib | 0.04 | uM | LJP5 | 1 | J06 | 72 | hr | 1235 | 4760 | 4119 | 1.1556 | 1.1736 |
MCF7 | Seliciclib | 0.04 | uM | LJP5 | 2 | J06 | 72 | hr | 1235 | 4880 | 4356 | 1.1202 | 1.1289 |
MCF7 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 1235 | 4855 | 4326 | 1.1222 | 1.1316 |
MCF7 | Seliciclib | 0.12 | uM | LJP5 | 1 | J05 | 72 | hr | 1235 | 4144 | 4119 | 1.0060 | 1.0069 |
MCF7 | Seliciclib | 0.12 | uM | LJP5 | 2 | J05 | 72 | hr | 1235 | 4195 | 4356 | 0.9630 | 0.9589 |
MCF7 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 1235 | 5017 | 4326 | 1.1596 | 1.1707 |
MCF7 | Seliciclib | 0.37 | uM | LJP5 | 1 | J04 | 72 | hr | 1235 | 3699 | 4119 | 0.8980 | 0.8799 |
MCF7 | Seliciclib | 0.37 | uM | LJP5 | 2 | J04 | 72 | hr | 1235 | 3684 | 4356 | 0.8457 | 0.8239 |
MCF7 | Seliciclib | 0.37 | uM | LJP5 | 3 | J04 | 72 | hr | 1235 | 3984 | 4326 | 0.9209 | 0.9109 |
MCF7 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 1235 | 3327 | 4119 | 0.8077 | 0.7686 |
MCF7 | Seliciclib | 1.11 | uM | LJP5 | 2 | J03 | 72 | hr | 1235 | 3514 | 4356 | 0.8067 | 0.7771 |
MCF7 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1235 | 3740 | 4326 | 0.8645 | 0.8452 |
MCF7 | Seliciclib | 3.33 | uM | LJP5 | 1 | J02 | 72 | hr | 1235 | 2738 | 4119 | 0.6647 | 0.5810 |
MCF7 | Seliciclib | 3.33 | uM | LJP5 | 2 | J02 | 72 | hr | 1235 | 3270 | 4356 | 0.7506 | 0.7081 |
MCF7 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 1235 | 3295 | 4326 | 0.7616 | 0.7204 |
MCF7 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 1235 | 734 | 4119 | 0.1782 | -0.2589 |
MCF7 | Seliciclib | 10 | uM | LJP5 | 2 | J01 | 72 | hr | 1235 | 687 | 4356 | 0.1577 | -0.2759 |
MCF7 | Seliciclib | 10 | uM | LJP5 | 3 | J01 | 72 | hr | 1235 | 697 | 4326 | 0.1611 | -0.2713 |
MCF7 | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 1235 | 3316 | 3974 | 0.8344 | 0.7963 |
MCF7 | AT-7519 | 0.04 | uM | LJP6 | 2 | K06 | 72 | hr | 1235 | 3573 | 4070 | 0.8778 | 0.8541 |
MCF7 | AT-7519 | 0.04 | uM | LJP6 | 3 | K06 | 72 | hr | 1235 | 3793 | 4126 | 0.9192 | 0.9055 |
MCF7 | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 1235 | 1412 | 3974 | 0.3553 | 0.0825 |
MCF7 | AT-7519 | 0.12 | uM | LJP6 | 2 | K05 | 72 | hr | 1235 | 1407 | 4070 | 0.3457 | 0.0786 |
MCF7 | AT-7519 | 0.12 | uM | LJP6 | 3 | K05 | 72 | hr | 1235 | 1370 | 4126 | 0.3320 | 0.0612 |
MCF7 | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 1235 | 890 | 3974 | 0.2240 | -0.1768 |