LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Seliciclib
0.04
uM
LJP5
1
J06
72
hr
1235 4760 4119 1.1556 1.1736
MCF7 Seliciclib
0.04
uM
LJP5
2
J06
72
hr
1235 4880 4356 1.1202 1.1289
MCF7 Seliciclib
0.04
uM
LJP5
3
J06
72
hr
1235 4855 4326 1.1222 1.1316
MCF7 Seliciclib
0.12
uM
LJP5
1
J05
72
hr
1235 4144 4119 1.0060 1.0069
MCF7 Seliciclib
0.12
uM
LJP5
2
J05
72
hr
1235 4195 4356 0.9630 0.9589
MCF7 Seliciclib
0.12
uM
LJP5
3
J05
72
hr
1235 5017 4326 1.1596 1.1707
MCF7 Seliciclib
0.37
uM
LJP5
1
J04
72
hr
1235 3699 4119 0.8980 0.8799
MCF7 Seliciclib
0.37
uM
LJP5
2
J04
72
hr
1235 3684 4356 0.8457 0.8239
MCF7 Seliciclib
0.37
uM
LJP5
3
J04
72
hr
1235 3984 4326 0.9209 0.9109
MCF7 Seliciclib
1.11
uM
LJP5
1
J03
72
hr
1235 3327 4119 0.8077 0.7686
MCF7 Seliciclib
1.11
uM
LJP5
2
J03
72
hr
1235 3514 4356 0.8067 0.7771
MCF7 Seliciclib
1.11
uM
LJP5
3
J03
72
hr
1235 3740 4326 0.8645 0.8452
MCF7 Seliciclib
3.33
uM
LJP5
1
J02
72
hr
1235 2738 4119 0.6647 0.5810
MCF7 Seliciclib
3.33
uM
LJP5
2
J02
72
hr
1235 3270 4356 0.7506 0.7081
MCF7 Seliciclib
3.33
uM
LJP5
3
J02
72
hr
1235 3295 4326 0.7616 0.7204
MCF7 Seliciclib
10
uM
LJP5
1
J01
72
hr
1235 734 4119 0.1782 -0.2589
MCF7 Seliciclib
10
uM
LJP5
2
J01
72
hr
1235 687 4356 0.1577 -0.2759
MCF7 Seliciclib
10
uM
LJP5
3
J01
72
hr
1235 697 4326 0.1611 -0.2713
MCF7 AT-7519
0.04
uM
LJP6
1
K06
72
hr
1235 3316 3974 0.8344 0.7963
MCF7 AT-7519
0.04
uM
LJP6
2
K06
72
hr
1235 3573 4070 0.8778 0.8541
MCF7 AT-7519
0.04
uM
LJP6
3
K06
72
hr
1235 3793 4126 0.9192 0.9055
MCF7 AT-7519
0.12
uM
LJP6
1
K05
72
hr
1235 1412 3974 0.3553 0.0825
MCF7 AT-7519
0.12
uM
LJP6
2
K05
72
hr
1235 1407 4070 0.3457 0.0786
MCF7 AT-7519
0.12
uM
LJP6
3
K05
72
hr
1235 1370 4126 0.3320 0.0612
MCF7 AT-7519
0.37
uM
LJP6
1
K04
72
hr
1235 890 3974 0.2240 -0.1768
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