LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Celastrol
0.37
uM
LJP6
 1
G10
 72
hr
 513 6266 10537 0.5946 0.7752
MCF 10A Celastrol
0.37
uM
LJP6
 2
G10
 72
hr
 513 6934 10386 0.6676 0.8221
MCF 10A Celastrol
0.37
uM
LJP6
 3
G10
 72
hr
 513 6033 10494 0.5749 0.7612
MCF 10A Celastrol
1.11
uM
LJP6
 1
G09
 72
hr
 513 620 10537 0.0588 0.0442
MCF 10A Celastrol
1.11
uM
LJP6
 2
G09
 72
hr
 513 534 10386 0.0514 0.0091
MCF 10A Celastrol
1.11
uM
LJP6
 3
G09
 72
hr
 513 612 10494 0.0583 0.0412
MCF 10A Celastrol
3.33
uM
LJP6
 1
G08
 72
hr
 513 369 10537 0.0350 -0.0729
MCF 10A Celastrol
3.33
uM
LJP6
 2
G08
 72
hr
 513 471 10386 0.0453 -0.0197
MCF 10A Celastrol
3.33
uM
LJP6
 3
G08
 72
hr
 513 511 10494 0.0487 -0.0011
MCF 10A Celastrol
10
uM
LJP6
 1
G07
 72
hr
 513 460 10537 0.0437 -0.0249
MCF 10A Celastrol
10
uM
LJP6
 2
G07
 72
hr
 513 615 10386 0.0592 0.0425
MCF 10A Celastrol
10
uM
LJP6
 3
G07
 72
hr
 513 500 10494 0.0476 -0.0060
MCF 10A SU11274
0.04
uM
LJP5
 1
J12
 72
hr
 513 10455 10254 1.0195 1.0090
MCF 10A SU11274
0.04
uM
LJP5
 2
J12
 72
hr
 513 10558 10349 1.0201 1.0092
MCF 10A SU11274
0.04
uM
LJP5
 3
J12
 72
hr
 513 10375 10483 0.9896 0.9952
MCF 10A SU11274
0.12
uM
LJP5
 1
J11
 72
hr
 513 9807 10254 0.9563 0.9794
MCF 10A SU11274
0.12
uM
LJP5
 2
J11
 72
hr
 513 10101 10349 0.9760 0.9888
MCF 10A SU11274
0.12
uM
LJP5
 3
J11
 72
hr
 513 10184 10483 0.9714 0.9867
MCF 10A SU11274
0.37
uM
LJP5
 1
J10
 72
hr
 513 9174 10254 0.8946 0.9491
MCF 10A SU11274
0.37
uM
LJP5
 2
J10
 72
hr
 513 9964 10349 0.9628 0.9826
MCF 10A SU11274
0.37
uM
LJP5
 3
J10
 72
hr
 513 9155 10483 0.8733 0.9387
MCF 10A SU11274
1.11
uM
LJP5
 1
J09
 72
hr
 513 7878 10254 0.7682 0.8816
MCF 10A SU11274
1.11
uM
LJP5
 2
J09
 72
hr
 513 8042 10349 0.7770 0.8869
MCF 10A SU11274
1.11
uM
LJP5
 3
J09
 72
hr
 513 7731 10483 0.7374 0.8648
MCF 10A SU11274
3.33
uM
LJP5
 1
J08
 72
hr
 513 5676 10254 0.5535 0.7441