LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A XMD16-144
0.37
uM
LJP5
 3
M10
 72
hr
 513 1347 10483 0.1285 0.2481
MCF 10A XMD16-144
1.11
uM
LJP5
 1
M09
 72
hr
 513 1177 10254 0.1148 0.2117
MCF 10A XMD16-144
1.11
uM
LJP5
 2
M09
 72
hr
 513 1437 10349 0.1389 0.2681
MCF 10A XMD16-144
1.11
uM
LJP5
 3
M09
 72
hr
 513 1295 10483 0.1235 0.2369
MCF 10A XMD16-144
3.33
uM
LJP5
 1
M08
 72
hr
 513 1406 10254 0.1371 0.2627
MCF 10A XMD16-144
3.33
uM
LJP5
 2
M08
 72
hr
 513 1353 10349 0.1307 0.2506
MCF 10A XMD16-144
3.33
uM
LJP5
 3
M08
 72
hr
 513 1133 10483 0.1081 0.1995
MCF 10A XMD16-144
10
uM
LJP5
 1
M07
 72
hr
 513 562 10254 0.0548 0.0212
MCF 10A XMD16-144
10
uM
LJP5
 2
M07
 72
hr
 513 791 10349 0.0764 0.1049
MCF 10A XMD16-144
10
uM
LJP5
 3
M07
 72
hr
 513 594 10483 0.0567 0.0341
MCF 10A Erlotinib
0.04
uM
LJP5
 1
M24
 72
hr
 513 9864 10254 0.9619 0.9821
MCF 10A Erlotinib
0.04
uM
LJP5
 2
M24
 72
hr
 513 9672 10349 0.9345 0.9690
MCF 10A Erlotinib
0.04
uM
LJP5
 3
M24
 72
hr
 513 10242 10483 0.9770 0.9893
MCF 10A Erlotinib
0.12
uM
LJP5
 1
M23
 72
hr
 513 8565 10254 0.8352 0.9184
MCF 10A Erlotinib
0.12
uM
LJP5
 2
M23
 72
hr
 513 8748 10349 0.8453 0.9239
MCF 10A Erlotinib
0.12
uM
LJP5
 3
M23
 72
hr
 513 8522 10483 0.8129 0.9070
MCF 10A Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 513 2292 10254 0.2235 0.4139
MCF 10A Erlotinib
0.37
uM
LJP5
 2
M22
 72
hr
 513 2089 10349 0.2018 0.3825
MCF 10A Erlotinib
0.37
uM
LJP5
 3
M22
 72
hr
 513 2690 10483 0.2566 0.4631
MCF 10A Erlotinib
1.11
uM
LJP5
 1
M21
 72
hr
 513 591 10254 0.0576 0.0331
MCF 10A Erlotinib
1.11
uM
LJP5
 2
M21
 72
hr
 513 667 10349 0.0644 0.0623
MCF 10A Erlotinib
1.11
uM
LJP5
 3
M21
 72
hr
 513 620 10483 0.0591 0.0443
MCF 10A Erlotinib
3.33
uM
LJP5
 1
M20
 72
hr
 513 616 10254 0.0601 0.0431
MCF 10A Erlotinib
3.33
uM
LJP5
 2
M20
 72
hr
 513 697 10349 0.0673 0.0731
MCF 10A Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 513 688 10483 0.0656 0.0696