LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 513 1289 10349 0.1246 0.2367
MCF 10A Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 513 1219 10483 0.1163 0.2198
MCF 10A Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 513 1350 10254 0.1317 0.2508
MCF 10A Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 513 1414 10349 0.1366 0.2634
MCF 10A Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 513 1364 10483 0.1301 0.2517
MCF 10A Barasertib
10
uM
LJP5
 1
D07
 72
hr
 513 1286 10254 0.1254 0.2368
MCF 10A Barasertib
10
uM
LJP5
 2
D07
 72
hr
 513 1230 10349 0.1189 0.2234
MCF 10A Barasertib
10
uM
LJP5
 3
D07
 72
hr
 513 1406 10483 0.1341 0.2605
MCF 10A Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 513 10165 10254 0.9912 0.9959
MCF 10A Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 513 9475 10349 0.9155 0.9597
MCF 10A Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 513 10489 10483 1.0005 1.0002
MCF 10A Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 513 10117 10254 0.9866 0.9938
MCF 10A Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 513 10016 10349 0.9678 0.9849
MCF 10A Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 513 10694 10483 1.0201 1.0092
MCF 10A Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 513 9491 10254 0.9255 0.9645
MCF 10A Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 513 9864 10349 0.9531 0.9779
MCF 10A Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 513 10524 10483 1.0039 1.0018
MCF 10A Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 513 8218 10254 0.8014 0.9001
MCF 10A Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 513 8492 10349 0.8205 0.9108
MCF 10A Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 513 8365 10483 0.7979 0.8989
MCF 10A Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 513 3867 10254 0.3771 0.5958
MCF 10A Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 513 4101 10349 0.3963 0.6153
MCF 10A Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 513 5325 10483 0.5079 0.7117
MCF 10A Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 513 1772 10254 0.1728 0.3321
MCF 10A Vemurafenib
10
uM
LJP5
 2
C13
 72
hr
 513 1862 10349 0.1799 0.3463