LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SB590885
3.33
uM
LJP5
 1
L14
 72
hr
 513 9267 10254 0.9037 0.9537
MCF 10A SB590885
3.33
uM
LJP5
 2
L14
 72
hr
 513 9660 10349 0.9334 0.9684
MCF 10A SB590885
3.33
uM
LJP5
 3
L14
 72
hr
 513 8896 10483 0.8486 0.9259
MCF 10A SB590885
10
uM
LJP5
 1
L13
 72
hr
 513 3992 10254 0.3893 0.6076
MCF 10A SB590885
10
uM
LJP5
 2
L13
 72
hr
 513 4366 10349 0.4219 0.6388
MCF 10A SB590885
10
uM
LJP5
 3
L13
 72
hr
 513 4143 10483 0.3952 0.6158
MCF 10A Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 513 5425 10537 0.5148 0.7175
MCF 10A Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 513 5198 10386 0.5004 0.7050
MCF 10A Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 513 4819 10494 0.4592 0.6726
MCF 10A Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 513 3540 10537 0.3359 0.5573
MCF 10A Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 513 3984 10386 0.3836 0.6037
MCF 10A Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 513 3804 10494 0.3625 0.5842
MCF 10A Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 513 2559 10537 0.2428 0.4455
MCF 10A Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 513 1931 10386 0.1859 0.3571
MCF 10A Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 513 2015 10494 0.1920 0.3690
MCF 10A Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 513 1382 10537 0.1312 0.2550
MCF 10A Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 513 1435 10386 0.1382 0.2674
MCF 10A Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 513 1396 10494 0.1330 0.2583
MCF 10A Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 513 948 10537 0.0900 0.1511
MCF 10A Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 513 1200 10386 0.1155 0.2162
MCF 10A Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 513 1165 10494 0.1110 0.2071
MCF 10A Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 513 714 10537 0.0678 0.0786
MCF 10A Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 513 602 10386 0.0580 0.0374
MCF 10A Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 513 796 10494 0.0758 0.1060
MCF 10A PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 513 4707 10254 0.4590 0.6701