LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 513 10691 10494 1.0187 1.0085
MCF 10A Imatinib
10
uM
LJP6
 1
N13
 72
hr
 513 11371 10537 1.0791 1.0352
MCF 10A Imatinib
10
uM
LJP6
 2
N13
 72
hr
 513 10917 10386 1.0510 1.0231
MCF 10A Imatinib
10
uM
LJP6
 3
N13
 72
hr
 513 10800 10494 1.0291 1.0132
MCF 10A NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 513 6685 10537 0.6344 0.8017
MCF 10A NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 513 6973 10386 0.6713 0.8245
MCF 10A NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 513 7193 10494 0.6854 0.8338
MCF 10A NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 513 3544 10537 0.3363 0.5577
MCF 10A NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 513 3259 10386 0.3138 0.5311
MCF 10A NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 513 3219 10494 0.3067 0.5245
MCF 10A NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 513 3385 10537 0.3212 0.5413
MCF 10A NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 513 2902 10386 0.2794 0.4907
MCF 10A NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 513 2547 10494 0.2427 0.4447
MCF 10A NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 513 2657 10537 0.2521 0.4581
MCF 10A NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 513 2496 10386 0.2403 0.4398
MCF 10A NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 513 2042 10494 0.1946 0.3732
MCF 10A NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 513 1458 10537 0.1384 0.2705
MCF 10A NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 513 1455 10386 0.1401 0.2714
MCF 10A NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 513 1503 10494 0.1432 0.2799
MCF 10A NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 513 870 10537 0.0826 0.1286
MCF 10A NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 513 932 10386 0.0897 0.1473
MCF 10A NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 513 787 10494 0.0750 0.1031
MCF 10A CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 513 472 10537 0.0448 -0.0191
MCF 10A CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 513 433 10386 0.0417 -0.0385
MCF 10A CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 513 723 10494 0.0689 0.0818