LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 513 4616 10349 0.4460 0.6600
MCF 10A PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 513 4538 10483 0.4329 0.6500
MCF 10A PD184352
0.12
uM
LJP5
 1
L11
 72
hr
 513 3087 10254 0.3010 0.5148
MCF 10A PD184352
0.12
uM
LJP5
 2
L11
 72
hr
 513 3099 10349 0.2994 0.5142
MCF 10A PD184352
0.12
uM
LJP5
 3
L11
 72
hr
 513 2516 10483 0.2400 0.4408
MCF 10A PD184352
0.37
uM
LJP5
 1
L10
 72
hr
 513 2206 10254 0.2151 0.4014
MCF 10A PD184352
0.37
uM
LJP5
 2
L10
 72
hr
 513 2279 10349 0.2202 0.4105
MCF 10A PD184352
0.37
uM
LJP5
 3
L10
 72
hr
 513 1936 10483 0.1847 0.3566
MCF 10A PD184352
1.11
uM
LJP5
 1
L09
 72
hr
 513 1458 10254 0.1422 0.2733
MCF 10A PD184352
1.11
uM
LJP5
 2
L09
 72
hr
 513 1801 10349 0.1740 0.3359
MCF 10A PD184352
1.11
uM
LJP5
 3
L09
 72
hr
 513 1371 10483 0.1308 0.2532
MCF 10A PD184352
3.33
uM
LJP5
 1
L08
 72
hr
 513 1119 10254 0.1091 0.1977
MCF 10A PD184352
3.33
uM
LJP5
 2
L08
 72
hr
 513 1144 10349 0.1105 0.2031
MCF 10A PD184352
3.33
uM
LJP5
 3
L08
 72
hr
 513 1233 10483 0.1176 0.2230
MCF 10A PD184352
10
uM
LJP5
 1
L07
 72
hr
 513 763 10254 0.0744 0.0961
MCF 10A PD184352
10
uM
LJP5
 2
L07
 72
hr
 513 797 10349 0.0770 0.1068
MCF 10A PD184352
10
uM
LJP5
 3
L07
 72
hr
 513 785 10483 0.0749 0.1025
MCF 10A PLX-4720
0.04
uM
LJP5
 1
K06
 72
hr
 513 10203 10254 0.9950 0.9977
MCF 10A PLX-4720
0.04
uM
LJP5
 2
K06
 72
hr
 513 10852 10349 1.0485 1.0220
MCF 10A PLX-4720
0.04
uM
LJP5
 3
K06
 72
hr
 513 10826 10483 1.0327 1.0148
MCF 10A PLX-4720
0.12
uM
LJP5
 1
K05
 72
hr
 513 11107 10254 1.0831 1.0373
MCF 10A PLX-4720
0.12
uM
LJP5
 2
K05
 72
hr
 513 11167 10349 1.0790 1.0354
MCF 10A PLX-4720
0.12
uM
LJP5
 3
K05
 72
hr
 513 10677 10483 1.0185 1.0084
MCF 10A PLX-4720
0.37
uM
LJP5
 1
K04
 72
hr
 513 11052 10254 1.0777 1.0350
MCF 10A PLX-4720
0.37
uM
LJP5
 2
K04
 72
hr
 513 11400 10349 1.1015 1.0451