LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Vemurafenib
10
uM
LJP5
 3
C13
 72
hr
 513 2077 10483 0.1981 0.3787
MCF 10A Enzastaurin
0.04
uM
LJP5
 1
D18
 72
hr
 513 10163 10254 0.9911 0.9958
MCF 10A Enzastaurin
0.04
uM
LJP5
 2
D18
 72
hr
 513 9719 10349 0.9391 0.9712
MCF 10A Enzastaurin
0.04
uM
LJP5
 3
D18
 72
hr
 513 10927 10483 1.0423 1.0191
MCF 10A Enzastaurin
0.12
uM
LJP5
 1
D17
 72
hr
 513 9984 10254 0.9736 0.9877
MCF 10A Enzastaurin
0.12
uM
LJP5
 2
D17
 72
hr
 513 9588 10349 0.9264 0.9650
MCF 10A Enzastaurin
0.12
uM
LJP5
 3
D17
 72
hr
 513 10582 10483 1.0094 1.0043
MCF 10A Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 513 9503 10254 0.9267 0.9651
MCF 10A Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 513 10054 10349 0.9714 0.9867
MCF 10A Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 513 10384 10483 0.9905 0.9956
MCF 10A Enzastaurin
1.11
uM
LJP5
 1
D15
 72
hr
 513 9451 10254 0.9216 0.9626
MCF 10A Enzastaurin
1.11
uM
LJP5
 2
D15
 72
hr
 513 9818 10349 0.9486 0.9758
MCF 10A Enzastaurin
1.11
uM
LJP5
 3
D15
 72
hr
 513 10783 10483 1.0286 1.0130
MCF 10A Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 513 9129 10254 0.8902 0.9469
MCF 10A Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 513 8367 10349 0.8084 0.9042
MCF 10A Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 513 9942 10483 0.9483 0.9758
MCF 10A Enzastaurin
10
uM
LJP5
 1
D13
 72
hr
 513 7265 10254 0.7085 0.8466
MCF 10A Enzastaurin
10
uM
LJP5
 2
D13
 72
hr
 513 7708 10349 0.7448 0.8685
MCF 10A Enzastaurin
10
uM
LJP5
 3
D13
 72
hr
 513 7904 10483 0.7539 0.8743
MCF 10A Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 513 7723 10537 0.7329 0.8624
MCF 10A Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 513 7721 10386 0.7433 0.8678
MCF 10A Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 513 7836 10494 0.7467 0.8702
MCF 10A Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 513 6208 10537 0.5891 0.7714
MCF 10A Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 513 6056 10386 0.5830 0.7662
MCF 10A Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 513 6492 10494 0.6186 0.7911