LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 513 4919 10537 0.4668 0.6793
MCF 10A Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 513 4613 10386 0.4441 0.6588
MCF 10A Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 513 5072 10494 0.4833 0.6924
MCF 10A Palbociclib
1.11
uM
LJP6
 1
E15
 72
hr
 513 3784 10537 0.3591 0.5812
MCF 10A Palbociclib
1.11
uM
LJP6
 2
E15
 72
hr
 513 3839 10386 0.3696 0.5900
MCF 10A Palbociclib
1.11
uM
LJP6
 3
E15
 72
hr
 513 3685 10494 0.3511 0.5726
MCF 10A Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 513 3538 10537 0.3357 0.5571
MCF 10A Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 513 3101 10386 0.2986 0.5137
MCF 10A Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 513 3369 10494 0.3210 0.5406
MCF 10A Palbociclib
10
uM
LJP6
 1
E13
 72
hr
 513 2407 10537 0.2284 0.4254
MCF 10A Palbociclib
10
uM
LJP6
 2
E13
 72
hr
 513 2246 10386 0.2162 0.4052
MCF 10A Palbociclib
10
uM
LJP6
 3
E13
 72
hr
 513 2532 10494 0.2413 0.4428
MCF 10A PF562271
0.04
uM
LJP6
 1
F18
 72
hr
 513 8675 10537 0.8232 0.9127
MCF 10A PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 513 8649 10386 0.8327 0.9174
MCF 10A PF562271
0.04
uM
LJP6
 3
F18
 72
hr
 513 8784 10494 0.8370 0.9199
MCF 10A PF562271
0.12
uM
LJP6
 1
F17
 72
hr
 513 6884 10537 0.6533 0.8139
MCF 10A PF562271
0.12
uM
LJP6
 2
F17
 72
hr
 513 7193 10386 0.6925 0.8376
MCF 10A PF562271
0.12
uM
LJP6
 3
F17
 72
hr
 513 7292 10494 0.6948 0.8395
MCF 10A PF562271
0.37
uM
LJP6
 1
F16
 72
hr
 513 4704 10537 0.4464 0.6622
MCF 10A PF562271
0.37
uM
LJP6
 2
F16
 72
hr
 513 4104 10386 0.3951 0.6147
MCF 10A PF562271
0.37
uM
LJP6
 3
F16
 72
hr
 513 5087 10494 0.4847 0.6935
MCF 10A PF562271
1.11
uM
LJP6
 1
F15
 72
hr
 513 1569 10537 0.1489 0.2921
MCF 10A PF562271
1.11
uM
LJP6
 2
F15
 72
hr
 513 1476 10386 0.1421 0.2756
MCF 10A PF562271
1.11
uM
LJP6
 3
F15
 72
hr
 513 2123 10494 0.2023 0.3855
MCF 10A PF562271
3.33
uM
LJP6
 1
F14
 72
hr
 513 649 10537 0.0616 0.0553