LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 513 10667 10349 1.0307 1.0140
MCF 10A Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 513 10555 10483 1.0068 1.0031
MCF 10A Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 513 10279 10254 1.0024 1.0011
MCF 10A Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 513 9871 10349 0.9538 0.9783
MCF 10A Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 513 9809 10483 0.9357 0.9697
MCF 10A Nilotinib
1.11
uM
LJP5
 1
N15
 72
hr
 513 10906 10254 1.0635 1.0287
MCF 10A Nilotinib
1.11
uM
LJP5
 2
N15
 72
hr
 513 11146 10349 1.0770 1.0345
MCF 10A Nilotinib
1.11
uM
LJP5
 3
N15
 72
hr
 513 10603 10483 1.0114 1.0052
MCF 10A Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 513 10575 10254 1.0312 1.0143
MCF 10A Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 513 10990 10349 1.0619 1.0279
MCF 10A Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 513 9793 10483 0.9341 0.9689
MCF 10A Nilotinib
10
uM
LJP5
 1
N13
 72
hr
 513 3889 10254 0.3792 0.5979
MCF 10A Nilotinib
10
uM
LJP5
 2
N13
 72
hr
 513 4406 10349 0.4257 0.6423
MCF 10A Nilotinib
10
uM
LJP5
 3
N13
 72
hr
 513 2998 10483 0.2860 0.5000
MCF 10A JNK-9L
0.04
uM
LJP6
 1
K24
 72
hr
 513 8900 10537 0.8446 0.9240
MCF 10A JNK-9L
0.04
uM
LJP6
 2
K24
 72
hr
 513 9039 10386 0.8702 0.9369
MCF 10A JNK-9L
0.04
uM
LJP6
 3
K24
 72
hr
 513 9117 10494 0.8687 0.9364
MCF 10A JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 513 7744 10537 0.7349 0.8636
MCF 10A JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 513 7641 10386 0.7356 0.8634
MCF 10A JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 513 7463 10494 0.7111 0.8494
MCF 10A JNK-9L
0.37
uM
LJP6
 1
K22
 72
hr
 513 3269 10537 0.3102 0.5291
MCF 10A JNK-9L
0.37
uM
LJP6
 2
K22
 72
hr
 513 2942 10386 0.2832 0.4954
MCF 10A JNK-9L
0.37
uM
LJP6
 3
K22
 72
hr
 513 3204 10494 0.3053 0.5229
MCF 10A JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 513 760 10537 0.0721 0.0942
MCF 10A JNK-9L
1.11
uM
LJP6
 2
K21
 72
hr
 513 831 10386 0.0800 0.1174