LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 513 9968 10483 0.9508 0.9770
MCF 10A NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 513 8580 10254 0.8367 0.9191
MCF 10A NVP-AEW541
0.12
uM
LJP5
 2
E17
 72
hr
 513 8514 10349 0.8226 0.9119
MCF 10A NVP-AEW541
0.12
uM
LJP5
 3
E17
 72
hr
 513 9354 10483 0.8923 0.9483
MCF 10A NVP-AEW541
0.37
uM
LJP5
 1
E16
 72
hr
 513 5092 10254 0.4966 0.7008
MCF 10A NVP-AEW541
0.37
uM
LJP5
 2
E16
 72
hr
 513 5607 10349 0.5418 0.7362
MCF 10A NVP-AEW541
0.37
uM
LJP5
 3
E16
 72
hr
 513 7302 10483 0.6965 0.8405
MCF 10A NVP-AEW541
1.11
uM
LJP5
 1
E15
 72
hr
 513 3033 10254 0.2958 0.5086
MCF 10A NVP-AEW541
1.11
uM
LJP5
 2
E15
 72
hr
 513 3070 10349 0.2966 0.5109
MCF 10A NVP-AEW541
1.11
uM
LJP5
 3
E15
 72
hr
 513 3933 10483 0.3752 0.5966
MCF 10A NVP-AEW541
3.33
uM
LJP5
 1
E14
 72
hr
 513 3110 10254 0.3033 0.5174
MCF 10A NVP-AEW541
3.33
uM
LJP5
 2
E14
 72
hr
 513 2731 10349 0.2639 0.4707
MCF 10A NVP-AEW541
3.33
uM
LJP5
 3
E14
 72
hr
 513 3220 10483 0.3072 0.5249
MCF 10A NVP-AEW541
10
uM
LJP5
 1
E13
 72
hr
 513 1200 10254 0.1170 0.2172
MCF 10A NVP-AEW541
10
uM
LJP5
 2
E13
 72
hr
 513 966 10349 0.0933 0.1571
MCF 10A NVP-AEW541
10
uM
LJP5
 3
E13
 72
hr
 513 1274 10483 0.1215 0.2323
MCF 10A PHA-665752
0.04
uM
LJP5
 1
F18
 72
hr
 513 9231 10254 0.9002 0.9519
MCF 10A PHA-665752
0.04
uM
LJP5
 2
F18
 72
hr
 513 10510 10349 1.0155 1.0071
MCF 10A PHA-665752
0.04
uM
LJP5
 3
F18
 72
hr
 513 10047 10483 0.9584 0.9806
MCF 10A PHA-665752
0.12
uM
LJP5
 1
F17
 72
hr
 513 9803 10254 0.9559 0.9793
MCF 10A PHA-665752
0.12
uM
LJP5
 2
F17
 72
hr
 513 10309 10349 0.9961 0.9982
MCF 10A PHA-665752
0.12
uM
LJP5
 3
F17
 72
hr
 513 10163 10483 0.9694 0.9858
MCF 10A PHA-665752
0.37
uM
LJP5
 1
F16
 72
hr
 513 9083 10254 0.8857 0.9446
MCF 10A PHA-665752
0.37
uM
LJP5
 2
F16
 72
hr
 513 10206 10349 0.9861 0.9936
MCF 10A PHA-665752
0.37
uM
LJP5
 3
F16
 72
hr
 513 9933 10483 0.9475 0.9754