LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PHA-665752
1.11
uM
LJP5
 1
F15
 72
hr
 513 9039 10254 0.8814 0.9424
MCF 10A PHA-665752
1.11
uM
LJP5
 2
F15
 72
hr
 513 9792 10349 0.9461 0.9746
MCF 10A PHA-665752
1.11
uM
LJP5
 3
F15
 72
hr
 513 9968 10483 0.9508 0.9770
MCF 10A PHA-665752
3.33
uM
LJP5
 1
F14
 72
hr
 513 9436 10254 0.9202 0.9619
MCF 10A PHA-665752
3.33
uM
LJP5
 2
F14
 72
hr
 513 9592 10349 0.9268 0.9652
MCF 10A PHA-665752
3.33
uM
LJP5
 3
F14
 72
hr
 513 9926 10483 0.9468 0.9750
MCF 10A PHA-665752
10
uM
LJP5
 1
F13
 72
hr
 513 599 10254 0.0584 0.0364
MCF 10A PHA-665752
10
uM
LJP5
 2
F13
 72
hr
 513 950 10349 0.0918 0.1526
MCF 10A PHA-665752
10
uM
LJP5
 3
F13
 72
hr
 513 503 10483 0.0480 -0.0047
MCF 10A PI103
0.04
uM
LJP6
 1
I18
 72
hr
 513 8202 10537 0.7783 0.8883
MCF 10A PI103
0.04
uM
LJP6
 2
I18
 72
hr
 513 8512 10386 0.8195 0.9103
MCF 10A PI103
0.04
uM
LJP6
 3
I18
 72
hr
 513 8013 10494 0.7635 0.8798
MCF 10A PI103
0.12
uM
LJP6
 1
I17
 72
hr
 513 4328 10537 0.4107 0.6307
MCF 10A PI103
0.12
uM
LJP6
 2
I17
 72
hr
 513 4121 10386 0.3968 0.6162
MCF 10A PI103
0.12
uM
LJP6
 3
I17
 72
hr
 513 3499 10494 0.3334 0.5540
MCF 10A PI103
0.37
uM
LJP6
 1
I16
 72
hr
 513 1693 10537 0.1607 0.3149
MCF 10A PI103
0.37
uM
LJP6
 2
I16
 72
hr
 513 1427 10386 0.1374 0.2657
MCF 10A PI103
0.37
uM
LJP6
 3
I16
 72
hr
 513 1324 10494 0.1262 0.2431
MCF 10A PI103
1.11
uM
LJP6
 1
I15
 72
hr
 513 1224 10537 0.1162 0.2206
MCF 10A PI103
1.11
uM
LJP6
 2
I15
 72
hr
 513 1123 10386 0.1081 0.1977
MCF 10A PI103
1.11
uM
LJP6
 3
I15
 72
hr
 513 836 10494 0.0797 0.1185
MCF 10A PI103
3.33
uM
LJP6
 1
I14
 72
hr
 513 836 10537 0.0793 0.1184
MCF 10A PI103
3.33
uM
LJP6
 2
I14
 72
hr
 513 743 10386 0.0715 0.0889
MCF 10A PI103
3.33
uM
LJP6
 3
I14
 72
hr
 513 855 10494 0.0815 0.1243
MCF 10A PI103
10
uM
LJP6
 1
I13
 72
hr
 513 778 10537 0.0738 0.1001