LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Buparlisib
0.04
uM
LJP5
 1
H06
 72
hr
 513 9726 10254 0.9484 0.9756
MCF 10A Buparlisib
0.04
uM
LJP5
 2
H06
 72
hr
 513 10388 10349 1.0037 1.0017
MCF 10A Buparlisib
0.04
uM
LJP5
 3
H06
 72
hr
 513 10074 10483 0.9609 0.9818
MCF 10A Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 513 8281 10254 0.8075 0.9034
MCF 10A Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 513 8474 10349 0.8188 0.9098
MCF 10A Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 513 8458 10483 0.8068 0.9037
MCF 10A Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 513 4493 10254 0.4381 0.6522
MCF 10A Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 513 5887 10349 0.5688 0.7559
MCF 10A Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 513 6299 10483 0.6008 0.7791
MCF 10A Buparlisib
1.11
uM
LJP5
 1
H03
 72
hr
 513 1277 10254 0.1245 0.2348
MCF 10A Buparlisib
1.11
uM
LJP5
 2
H03
 72
hr
 513 1229 10349 0.1188 0.2232
MCF 10A Buparlisib
1.11
uM
LJP5
 3
H03
 72
hr
 513 1565 10483 0.1493 0.2919
MCF 10A Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 513 318 10254 0.0310 -0.1049
MCF 10A Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 513 357 10349 0.0345 -0.0804
MCF 10A Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 513 483 10483 0.0461 -0.0139
MCF 10A Buparlisib
10
uM
LJP5
 1
H01
 72
hr
 513 344 10254 0.0335 -0.0885
MCF 10A Buparlisib
10
uM
LJP5
 2
H01
 72
hr
 513 307 10349 0.0297 -0.1119
MCF 10A Buparlisib
10
uM
LJP5
 3
H01
 72
hr
 513 343 10483 0.0327 -0.0885
MCF 10A XL147
0.04
uM
LJP5
 1
G12
 72
hr
 513 10599 10254 1.0336 1.0153
MCF 10A XL147
0.04
uM
LJP5
 2
G12
 72
hr
 513 11032 10349 1.0659 1.0297
MCF 10A XL147
0.04
uM
LJP5
 3
G12
 72
hr
 513 10450 10483 0.9968 0.9985
MCF 10A XL147
0.12
uM
LJP5
 1
G11
 72
hr
 513 9518 10254 0.9282 0.9658
MCF 10A XL147
0.12
uM
LJP5
 2
G11
 72
hr
 513 10170 10349 0.9827 0.9919
MCF 10A XL147
0.12
uM
LJP5
 3
G11
 72
hr
 513 10811 10483 1.0312 1.0142
MCF 10A XL147
0.37
uM
LJP5
 1
G10
 72
hr
 513 9718 10254 0.9477 0.9753