LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Erlotinib
10
uM
LJP5
 1
M19
 72
hr
 513 829 10254 0.0808 0.1173
MCF 10A Erlotinib
10
uM
LJP5
 2
M19
 72
hr
 513 794 10349 0.0767 0.1059
MCF 10A Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 513 696 10483 0.0664 0.0724
MCF 10A Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 513 7152 10537 0.6787 0.8299
MCF 10A Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 513 7186 10386 0.6918 0.8372
MCF 10A Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 513 6864 10494 0.6540 0.8142
MCF 10A Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 513 3238 10537 0.3073 0.5257
MCF 10A Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 513 2810 10386 0.2705 0.4797
MCF 10A Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 513 2111 10494 0.2012 0.3837
MCF 10A Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 513 1092 10537 0.1036 0.1890
MCF 10A Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 513 997 10386 0.0960 0.1653
MCF 10A Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 513 972 10494 0.0926 0.1579
MCF 10A Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 513 923 10537 0.0876 0.1440
MCF 10A Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 513 817 10386 0.0787 0.1130
MCF 10A Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 513 850 10494 0.0810 0.1228
MCF 10A Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 513 919 10537 0.0872 0.1429
MCF 10A Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 513 760 10386 0.0732 0.0946
MCF 10A Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 513 680 10494 0.0648 0.0667
MCF 10A Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 513 840 10537 0.0797 0.1196
MCF 10A Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 513 833 10386 0.0802 0.1180
MCF 10A Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 513 800 10494 0.0762 0.1073
MCF 10A Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 513 11011 10254 1.0737 1.0332
MCF 10A Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 513 11221 10349 1.0842 1.0377
MCF 10A Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 513 10551 10483 1.0064 1.0029
MCF 10A Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 513 10605 10254 1.0342 1.0156