LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 513 1543 10537 0.1464 0.2872
MCF 10A WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 513 1419 10386 0.1366 0.2641
MCF 10A WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 513 1451 10494 0.1383 0.2696
MCF 10A WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 513 1383 10537 0.1312 0.2552
MCF 10A WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 513 1345 10386 0.1295 0.2486
MCF 10A WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 513 1182 10494 0.1126 0.2111
MCF 10A WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 513 947 10537 0.0899 0.1508
MCF 10A WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 513 1149 10386 0.1106 0.2041
MCF 10A WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 513 1027 10494 0.0979 0.1727
MCF 10A WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 513 917 10537 0.0870 0.1423
MCF 10A WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 513 903 10386 0.0869 0.1390
MCF 10A WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 513 869 10494 0.0828 0.1285
MCF 10A WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 513 949 10537 0.0901 0.1514
MCF 10A WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 513 666 10386 0.0641 0.0618
MCF 10A WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 513 1031 10494 0.0982 0.1737
MCF 10A Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 513 1321 10254 0.1288 0.2446
MCF 10A Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 513 1433 10349 0.1385 0.2673
MCF 10A Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 513 1469 10483 0.1401 0.2733
MCF 10A Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 513 1414 10254 0.1379 0.2643
MCF 10A Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 513 1227 10349 0.1186 0.2227
MCF 10A Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 513 1359 10483 0.1296 0.2507
MCF 10A Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 513 1282 10254 0.1250 0.2360
MCF 10A Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 513 1385 10349 0.1338 0.2574
MCF 10A Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 513 1274 10483 0.1215 0.2323
MCF 10A Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 513 1296 10254 0.1264 0.2391