LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 513 10345 10349 0.9996 0.9998
MCF 10A Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 513 9667 10483 0.9221 0.9631
MCF 10A Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 513 9589 10254 0.9351 0.9692
MCF 10A Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 513 9636 10349 0.9311 0.9673
MCF 10A Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 513 9202 10483 0.8778 0.9410
MCF 10A Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 513 7969 10254 0.7771 0.8866
MCF 10A Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 513 7960 10349 0.7691 0.8824
MCF 10A Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 513 7430 10483 0.7087 0.8479
MCF 10A Fedratinib
3.33
uM
LJP5
 1
L02
 72
hr
 513 1566 10254 0.1527 0.2946
MCF 10A Fedratinib
3.33
uM
LJP5
 2
L02
 72
hr
 513 1734 10349 0.1675 0.3243
MCF 10A Fedratinib
3.33
uM
LJP5
 3
L02
 72
hr
 513 1697 10483 0.1619 0.3162
MCF 10A Fedratinib
10
uM
LJP5
 1
L01
 72
hr
 513 530 10254 0.0517 0.0074
MCF 10A Fedratinib
10
uM
LJP5
 2
L01
 72
hr
 513 578 10349 0.0558 0.0277
MCF 10A Fedratinib
10
uM
LJP5
 3
L01
 72
hr
 513 604 10483 0.0576 0.0381
MCF 10A Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 513 626 10254 0.0610 0.0470
MCF 10A Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 513 677 10349 0.0654 0.0659
MCF 10A Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 513 723 10483 0.0690 0.0819
MCF 10A Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 513 741 10254 0.0723 0.0887
MCF 10A Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 513 791 10349 0.0764 0.1049
MCF 10A Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 513 817 10483 0.0779 0.1127
MCF 10A Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 513 698 10254 0.0681 0.0737
MCF 10A Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 513 761 10349 0.0735 0.0951
MCF 10A Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 513 752 10483 0.0717 0.0917
MCF 10A Trametinib
1.11
uM
LJP5
 1
P21
 72
hr
 513 801 10254 0.0781 0.1085
MCF 10A Trametinib
1.11
uM
LJP5
 2
P21
 72
hr
 513 740 10349 0.0715 0.0880