LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Trametinib
1.11
uM
LJP5
 3
P21
 72
hr
 513 1099 10483 0.1048 0.1911
MCF 10A Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 513 932 10254 0.0909 0.1480
MCF 10A Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 513 851 10349 0.0822 0.1237
MCF 10A Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 513 948 10483 0.0904 0.1514
MCF 10A Trametinib
10
uM
LJP5
 1
P19
 72
hr
 513 1075 10254 0.1048 0.1866
MCF 10A Trametinib
10
uM
LJP5
 2
P19
 72
hr
 513 988 10349 0.0955 0.1631
MCF 10A Trametinib
10
uM
LJP5
 3
P19
 72
hr
 513 999 10483 0.0953 0.1653
MCF 10A Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 513 760 10537 0.0721 0.0942
MCF 10A Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 513 644 10386 0.0620 0.0536
MCF 10A Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 513 739 10494 0.0704 0.0873
MCF 10A Omipalisib
0.12
uM
LJP6
 1
N05
 72
hr
 513 657 10537 0.0623 0.0582
MCF 10A Omipalisib
0.12
uM
LJP6
 2
N05
 72
hr
 513 515 10386 0.0496 0.0007
MCF 10A Omipalisib
0.12
uM
LJP6
 3
N05
 72
hr
 513 650 10494 0.0619 0.0557
MCF 10A Omipalisib
0.37
uM
LJP6
 1
N04
 72
hr
 513 502 10537 0.0476 -0.0051
MCF 10A Omipalisib
0.37
uM
LJP6
 2
N04
 72
hr
 513 545 10386 0.0525 0.0139
MCF 10A Omipalisib
0.37
uM
LJP6
 3
N04
 72
hr
 513 561 10494 0.0535 0.0206
MCF 10A Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 513 497 10537 0.0472 -0.0074
MCF 10A Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 513 586 10386 0.0564 0.0310
MCF 10A Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 513 547 10494 0.0521 0.0147
MCF 10A Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 513 418 10537 0.0397 -0.0460
MCF 10A Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 513 450 10386 0.0433 -0.0299
MCF 10A Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 513 425 10494 0.0405 -0.0425
MCF 10A Omipalisib
10
uM
LJP6
 1
N01
 72
hr
 513 400 10537 0.0380 -0.0556
MCF 10A Omipalisib
10
uM
LJP6
 2
N01
 72
hr
 513 373 10386 0.0359 -0.0710
MCF 10A Omipalisib
10
uM
LJP6
 3
N01
 72
hr
 513 419 10494 0.0399 -0.0456