LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Brivanib
1.11
uM
LJP5
 1
P15
 72
hr
 513 6979 10254 0.6806 0.8296
MCF 10A Brivanib
1.11
uM
LJP5
 2
P15
 72
hr
 513 6954 10349 0.6719 0.8247
MCF 10A Brivanib
1.11
uM
LJP5
 3
P15
 72
hr
 513 7884 10483 0.7520 0.8732
MCF 10A Brivanib
3.33
uM
LJP5
 1
P14
 72
hr
 513 3961 10254 0.3863 0.6047
MCF 10A Brivanib
3.33
uM
LJP5
 2
P14
 72
hr
 513 4977 10349 0.4809 0.6891
MCF 10A Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 513 4986 10483 0.4756 0.6860
MCF 10A Brivanib
10
uM
LJP5
 1
P13
 72
hr
 513 1462 10254 0.1426 0.2741
MCF 10A Brivanib
10
uM
LJP5
 2
P13
 72
hr
 513 1444 10349 0.1395 0.2695
MCF 10A Brivanib
10
uM
LJP5
 3
P13
 72
hr
 513 1533 10483 0.1462 0.2858
MCF 10A CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 513 10390 10537 0.9860 0.9935
MCF 10A CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 513 10104 10386 0.9728 0.9873
MCF 10A CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 513 9443 10494 0.8998 0.9521
MCF 10A CHIR-99021
0.12
uM
LJP6
 1
P17
 72
hr
 513 9993 10537 0.9483 0.9758
MCF 10A CHIR-99021
0.12
uM
LJP6
 2
P17
 72
hr
 513 9665 10386 0.9305 0.9671
MCF 10A CHIR-99021
0.12
uM
LJP6
 3
P17
 72
hr
 513 9054 10494 0.8627 0.9333
MCF 10A CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 513 8927 10537 0.8471 0.9253
MCF 10A CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 513 8607 10386 0.8286 0.9152
MCF 10A CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 513 8614 10494 0.8208 0.9113
MCF 10A CHIR-99021
1.11
uM
LJP6
 1
P15
 72
hr
 513 7533 10537 0.7149 0.8518
MCF 10A CHIR-99021
1.11
uM
LJP6
 2
P15
 72
hr
 513 6447 10386 0.6207 0.7918
MCF 10A CHIR-99021
1.11
uM
LJP6
 3
P15
 72
hr
 513 6334 10494 0.6035 0.7810
MCF 10A CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 513 6494 10537 0.6163 0.7898
MCF 10A CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 513 5837 10386 0.5620 0.7512
MCF 10A CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 513 6015 10494 0.5732 0.7600
MCF 10A CHIR-99021
10
uM
LJP6
 1
P13
 72
hr
 513 5280 10537 0.5011 0.7068