LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A LDN-193189
10
uM
LJP5
 3
G01
 72
hr
 513 114 10483 0.0109 -0.2923
MCF 10A PF431396
0.04
uM
LJP5
 1
E12
 72
hr
 513 6077 10254 0.5926 0.7719
MCF 10A PF431396
0.04
uM
LJP5
 2
E12
 72
hr
 513 6002 10349 0.5799 0.7637
MCF 10A PF431396
0.04
uM
LJP5
 3
E12
 72
hr
 513 6403 10483 0.6108 0.7858
MCF 10A PF431396
0.12
uM
LJP5
 1
E11
 72
hr
 513 2286 10254 0.2229 0.4130
MCF 10A PF431396
0.12
uM
LJP5
 2
E11
 72
hr
 513 2577 10349 0.2490 0.4511
MCF 10A PF431396
0.12
uM
LJP5
 3
E11
 72
hr
 513 3054 10483 0.2913 0.5064
MCF 10A PF431396
0.37
uM
LJP5
 1
E10
 72
hr
 513 1232 10254 0.1201 0.2246
MCF 10A PF431396
0.37
uM
LJP5
 2
E10
 72
hr
 513 1237 10349 0.1195 0.2250
MCF 10A PF431396
0.37
uM
LJP5
 3
E10
 72
hr
 513 1082 10483 0.1032 0.1869
MCF 10A PF431396
1.11
uM
LJP5
 1
E09
 72
hr
 513 750 10254 0.0731 0.0917
MCF 10A PF431396
1.11
uM
LJP5
 2
E09
 72
hr
 513 828 10349 0.0800 0.1166
MCF 10A PF431396
1.11
uM
LJP5
 3
E09
 72
hr
 513 981 10483 0.0936 0.1604
MCF 10A PF431396
3.33
uM
LJP5
 1
E08
 72
hr
 513 744 10254 0.0726 0.0897
MCF 10A PF431396
3.33
uM
LJP5
 2
E08
 72
hr
 513 683 10349 0.0660 0.0681
MCF 10A PF431396
3.33
uM
LJP5
 3
E08
 72
hr
 513 856 10483 0.0817 0.1247
MCF 10A PF431396
10
uM
LJP5
 1
E07
 72
hr
 513 557 10254 0.0543 0.0191
MCF 10A PF431396
10
uM
LJP5
 2
E07
 72
hr
 513 694 10349 0.0671 0.0720
MCF 10A PF431396
10
uM
LJP5
 3
E07
 72
hr
 513 526 10483 0.0502 0.0056
MCF 10A Celastrol
0.04
uM
LJP6
 1
G12
 72
hr
 513 10870 10537 1.0315 1.0143
MCF 10A Celastrol
0.04
uM
LJP6
 2
G12
 72
hr
 513 11882 10386 1.1439 1.0630
MCF 10A Celastrol
0.04
uM
LJP6
 3
G12
 72
hr
 513 11985 10494 1.1420 1.0619
MCF 10A Celastrol
0.12
uM
LJP6
 1
G11
 72
hr
 513 11243 10537 1.0669 1.0299
MCF 10A Celastrol
0.12
uM
LJP6
 2
G11
 72
hr
 513 11871 10386 1.1429 1.0625
MCF 10A Celastrol
0.12
uM
LJP6
 3
G11
 72
hr
 513 12164 10494 1.1591 1.0690