LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 868 2849 3505 0.8127 0.8043
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 868 2569 3440 0.7467 0.7266
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 1
N15
 72
hr
 868 2077 3286 0.6320 0.5750
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 2
N15
 72
hr
 868 2656 3505 0.7577 0.7425
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 3
N15
 72
hr
 868 2210 3440 0.6424 0.6006
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 868 2179 3286 0.6631 0.6148
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 868 2613 3505 0.7454 0.7285
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 868 2338 3440 0.6796 0.6466
MDA-MB-231 Nilotinib
10
uM
LJP5
 1
N13
 72
hr
 868 1123 3286 0.3417 0.1434
MDA-MB-231 Nilotinib
10
uM
LJP5
 2
N13
 72
hr
 868 1339 3505 0.3820 0.2401
MDA-MB-231 Nilotinib
10
uM
LJP5
 3
N13
 72
hr
 868 1245 3440 0.3619 0.1990
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 1
K24
 72
hr
 868 2593 3429 0.7560 0.7368
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 2
K24
 72
hr
 868 2546 3652 0.6972 0.6805
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 3
K24
 72
hr
 868 2724 3587 0.7594 0.7483
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 868 2575 3429 0.7508 0.7307
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 868 2562 3652 0.7015 0.6856
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 868 2261 3587 0.6303 0.5962
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 1
K22
 72
hr
 868 2091 3429 0.6097 0.5581
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 2
K22
 72
hr
 868 2105 3652 0.5764 0.5332
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 3
K22
 72
hr
 868 1803 3587 0.5026 0.4291
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 868 1083 3429 0.3158 0.1180
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 2
K21
 72
hr
 868 1308 3652 0.3582 0.2187
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 3
K21
 72
hr
 868 1278 3587 0.3563 0.2080
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 1
K20
 72
hr
 868 815 3429 0.2376 -0.0314
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 2
K20
 72
hr
 868 842 3652 0.2306 -0.0146