LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 1
E15
 72
hr
 868 1739 3429 0.5070 0.4198
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 2
E15
 72
hr
 868 1647 3652 0.4510 0.3620
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 3
E15
 72
hr
 868 1658 3587 0.4622 0.3718
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 868 1651 3429 0.4814 0.3831
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 868 1411 3652 0.3864 0.2641
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 868 1690 3587 0.4711 0.3846
MDA-MB-231 Palbociclib
10
uM
LJP6
 1
E13
 72
hr
 868 1461 3429 0.4260 0.3003
MDA-MB-231 Palbociclib
10
uM
LJP6
 2
E13
 72
hr
 868 1462 3652 0.4003 0.2859
MDA-MB-231 Palbociclib
10
uM
LJP6
 3
E13
 72
hr
 868 1548 3587 0.4315 0.3265
MDA-MB-231 PF562271
0.04
uM
LJP6
 1
F18
 72
hr
 868 3393 3429 0.9893 0.9892
MDA-MB-231 PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 868 3016 3652 0.8259 0.8236
MDA-MB-231 PF562271
0.04
uM
LJP6
 3
F18
 72
hr
 868 3300 3587 0.9199 0.9201
MDA-MB-231 PF562271
0.12
uM
LJP6
 1
F17
 72
hr
 868 3416 3429 0.9960 0.9959
MDA-MB-231 PF562271
0.12
uM
LJP6
 2
F17
 72
hr
 868 2839 3652 0.7774 0.7712
MDA-MB-231 PF562271
0.12
uM
LJP6
 3
F17
 72
hr
 868 2974 3587 0.8290 0.8250
MDA-MB-231 PF562271
0.37
uM
LJP6
 1
F16
 72
hr
 868 2960 3429 0.8630 0.8568
MDA-MB-231 PF562271
0.37
uM
LJP6
 2
F16
 72
hr
 868 2797 3652 0.7659 0.7585
MDA-MB-231 PF562271
0.37
uM
LJP6
 3
F16
 72
hr
 868 2674 3587 0.7454 0.7326
MDA-MB-231 PF562271
1.11
uM
LJP6
 1
F15
 72
hr
 868 2378 3429 0.6933 0.6626
MDA-MB-231 PF562271
1.11
uM
LJP6
 2
F15
 72
hr
 868 2371 3652 0.6492 0.6238
MDA-MB-231 PF562271
1.11
uM
LJP6
 3
F15
 72
hr
 868 2399 3587 0.6688 0.6431
MDA-MB-231 PF562271
3.33
uM
LJP6
 1
F14
 72
hr
 868 1425 3429 0.4155 0.2841
MDA-MB-231 PF562271
3.33
uM
LJP6
 2
F14
 72
hr
 868 1376 3652 0.3768 0.2489
MDA-MB-231 PF562271
3.33
uM
LJP6
 3
F14
 72
hr
 868 1354 3587 0.3774 0.2425
MDA-MB-231 PF562271
10
uM
LJP6
 1
F13
 72
hr
 868 889 3429 0.2592 0.0121