LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 3
D18
 72
hr
 868 3895 3440 1.1322 1.1290
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 1
D17
 72
hr
 868 3287 3286 1.0002 1.0002
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 2
D17
 72
hr
 868 3270 3505 0.9328 0.9321
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 3
D17
 72
hr
 868 3700 3440 1.0755 1.0746
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 868 3563 3286 1.0842 1.0860
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 868 3208 3505 0.9152 0.9139
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 868 3656 3440 1.0627 1.0622
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 1
D15
 72
hr
 868 3654 3286 1.1119 1.1136
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 2
D15
 72
hr
 868 3288 3505 0.9380 0.9374
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 3
D15
 72
hr
 868 3673 3440 1.0676 1.0670
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 868 3555 3286 1.0818 1.0835
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 868 3122 3505 0.8906 0.8882
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 868 3772 3440 1.0964 1.0949
MDA-MB-231 Enzastaurin
10
uM
LJP5
 1
D13
 72
hr
 868 3224 3286 0.9811 0.9802
MDA-MB-231 Enzastaurin
10
uM
LJP5
 2
D13
 72
hr
 868 3329 3505 0.9497 0.9494
MDA-MB-231 Enzastaurin
10
uM
LJP5
 3
D13
 72
hr
 868 3238 3440 0.9412 0.9399
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 868 2687 3429 0.7834 0.7683
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 868 2760 3652 0.7558 0.7472
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 868 2674 3587 0.7454 0.7326
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 868 2447 3429 0.7135 0.6868
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 868 2402 3652 0.6577 0.6340
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 868 2166 3587 0.6038 0.5631
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 868 2125 3429 0.6196 0.5709
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 868 1868 3652 0.5115 0.4473
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 868 1931 3587 0.5383 0.4778