LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PD184352
0.12
uM
LJP5
 2
L11
 72
hr
 868 3221 3505 0.9189 0.9177
MDA-MB-231 PD184352
0.12
uM
LJP5
 3
L11
 72
hr
 868 2809 3440 0.8165 0.8060
MDA-MB-231 PD184352
0.37
uM
LJP5
 1
L10
 72
hr
 868 2542 3286 0.7735 0.7497
MDA-MB-231 PD184352
0.37
uM
LJP5
 2
L10
 72
hr
 868 2812 3505 0.8022 0.7926
MDA-MB-231 PD184352
0.37
uM
LJP5
 3
L10
 72
hr
 868 2470 3440 0.7180 0.6928
MDA-MB-231 PD184352
1.11
uM
LJP5
 1
L09
 72
hr
 868 1948 3286 0.5928 0.5233
MDA-MB-231 PD184352
1.11
uM
LJP5
 2
L09
 72
hr
 868 2384 3505 0.6801 0.6515
MDA-MB-231 PD184352
1.11
uM
LJP5
 3
L09
 72
hr
 868 2065 3440 0.6002 0.5468
MDA-MB-231 PD184352
3.33
uM
LJP5
 1
L08
 72
hr
 868 1704 3286 0.5185 0.4207
MDA-MB-231 PD184352
3.33
uM
LJP5
 2
L08
 72
hr
 868 1889 3505 0.5389 0.4712
MDA-MB-231 PD184352
3.33
uM
LJP5
 3
L08
 72
hr
 868 1992 3440 0.5790 0.5191
MDA-MB-231 PD184352
10
uM
LJP5
 1
L07
 72
hr
 868 1373 3286 0.4178 0.2696
MDA-MB-231 PD184352
10
uM
LJP5
 2
L07
 72
hr
 868 1305 3505 0.3723 0.2244
MDA-MB-231 PD184352
10
uM
LJP5
 3
L07
 72
hr
 868 1401 3440 0.4072 0.2724
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 1
K06
 72
hr
 868 3383 3286 1.0294 1.0304
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 2
K06
 72
hr
 868 3816 3505 1.0886 1.0861
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 3
K06
 72
hr
 868 3351 3440 0.9741 0.9737
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 1
K05
 72
hr
 868 3460 3286 1.0529 1.0544
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 2
K05
 72
hr
 868 3864 3505 1.1023 1.0991
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 3
K05
 72
hr
 868 3516 3440 1.0220 1.0220
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 1
K04
 72
hr
 868 3520 3286 1.0711 1.0728
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 2
K04
 72
hr
 868 3729 3505 1.0638 1.0624
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 3
K04
 72
hr
 868 3236 3440 0.9406 0.9393
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 1
K03
 72
hr
 868 2844 3286 0.8654 0.8550
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 868 3025 3505 0.8630 0.8588