LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SB590885
10
uM
LJP5
 1
L13
 72
hr
 868 677 3286 0.2060 -0.1214
MDA-MB-231 SB590885
10
uM
LJP5
 2
L13
 72
hr
 868 802 3505 0.2288 -0.0386
MDA-MB-231 SB590885
10
uM
LJP5
 3
L13
 72
hr
 868 640 3440 0.1860 -0.1423
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 868 2450 3429 0.7143 0.6878
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 868 2473 3652 0.6772 0.6571
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 868 2580 3587 0.7192 0.7025
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 868 2563 3429 0.7473 0.7266
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 868 2710 3652 0.7421 0.7319
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 868 2562 3587 0.7142 0.6967
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 868 2563 3429 0.7473 0.7266
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 868 2550 3652 0.6983 0.6818
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 868 2720 3587 0.7582 0.7471
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 868 2369 3429 0.6907 0.6594
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 868 2681 3652 0.7341 0.7229
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 868 2577 3587 0.7184 0.7016
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 868 2648 3429 0.7721 0.7553
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 868 2612 3652 0.7152 0.7014
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 868 2392 3587 0.6668 0.6408
MDA-MB-231 Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 868 1884 3429 0.5493 0.4783
MDA-MB-231 Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 868 1727 3652 0.4729 0.3935
MDA-MB-231 Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 868 1808 3587 0.5040 0.4311
MDA-MB-231 PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 868 3408 3286 1.0370 1.0382
MDA-MB-231 PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 868 3714 3505 1.0595 1.0582
MDA-MB-231 PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 868 3639 3440 1.0578 1.0573
MDA-MB-231 PD184352
0.12
uM
LJP5
 1
L11
 72
hr
 868 2842 3286 0.8648 0.8543